Description

tert-Butyl 2-(tert-Butoxycarbonylamino)Hex-5-Enoate is a high-purity, protected amino acid derivative featuring both a tert-butyl ester and a Boc-protected amine group. This compound is a critical pharmaceutical intermediate and versatile building block in organic synthesis, enabling the controlled introduction of functionalized amino acid motifs. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors, particularly for developing peptide-based therapeutics and novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex peptide drugs and protease inhibitors.
• Peptide Synthesis: Serves as a protected amino acid derivative for solid-phase and solution-phase peptide coupling reactions.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies and the development of novel bioactive molecules.
• Chemical Biology: Employed in the synthesis of labeled peptides and probes for biochemical research.
• Custom Synthesis: A starting material for the tailored production of specialized amino acid analogs and chiral compounds.
• API Development: Integral in the research and scale-up phases of new active pharmaceutical ingredient manufacturing.

Basic Information

Product Name	tert-Butyl 2-(tert-Butoxycarbonylamino)Hex-5-Enoate
CAS No.	151294-93-8
Molecular Formula	C₁₅H₂₇NO₄
Molecular Weight	285.38 g/mol
Synonyms	Boc-5-Hexenylglycine tert-Butyl Ester; 2-[(tert-Butoxycarbonyl)amino]hex-5-enoic acid tert-butyl ester; 5-Hexenylglycine, N-Boc-, tert-butyl ester; tert-Butyl N-(tert-butoxycarbonyl)-5-hexenylglycinate; (tert-Butoxycarbonylamino)hex-5-enoic Acid tert-Butyl Ester; Boc-DL-2-Amino-5-hexenoic acid tert-butyl ester; N-Boc-2-Amino-5-hexenoic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 2-(tert-Butoxycarbonylamino)Hex-5-Enoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure compliance with exacting standards for research and pharmaceutical use. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This compound is hygroscopic (moisture-sensitive); ensure containers are sealed under an inert atmosphere after each use to prevent degradation. Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.