Description

Spiro1,3-Dioxolane-4,6-6Hfuro3,2-D1,3Dioxin, 4,4A-Dihydro-2,2,2,2-Tetramethyl-7-(Methylthio)Methoxy-, (4As-Cis)- is a specialized spirocyclic compound with a complex molecular architecture, serving as a high-value synthetic intermediate. Its unique fused dioxolane and dioxin ring system, functionalized with a (methylthio)methoxy group, makes it a critical building block for advanced organic synthesis. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical sectors for constructing novel molecular scaffolds with targeted biological activity.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and antiviral therapies.
• Agrochemical Research: Used in developing new generations of pesticides and herbicides, leveraging its complex heterocyclic core.
• Material Science: Building block for specialty polymers and advanced organic electronic materials requiring specific stereochemistry and functional groups.
• Asymmetric Synthesis: Chiral synthon for constructing enantiomerically pure compounds in fine chemical and catalyst development.
• Chemical Biology: Probe or linker molecule in bioconjugation and the development of chemical tools for biological studies.

Basic Information

Product Name	Spiro1,3-Dioxolane-4,6-6Hfuro3,2-D1,3Dioxin, 4,4A-Dihydro-2,2,2,2-Tetramethyl-7-(Methylthio)Methoxy-, (4As-Cis)-
CAS No.	151252-16-3
Molecular Formula	C12H18O5S
Molecular Weight	274.33 g/mol
Synonyms	(4aS-cis)-4,4a-Dihydro-2,2,2,2-tetramethyl-7-[(methylthio)methoxy]spiro[1,3-dioxolane-4,6'-[6H]furo[3,2-d][1,3]dioxin]; 7-[(Methylthio)methoxy]-2,2,2,2-tetramethyl-4,4a-dihydro-spiro[1,3-dioxolane-4,6'-furo[3,2-d][1,3]dioxin] (4aS-cis); Spiro[1,3-dioxolane-4,6'-[6H]furo[3,2-d][1,3]dioxin], 4,4a-dihydro-2,2,2,2-tetramethyl-7-[(methylthio)methoxy]-, (4aS-cis)-; cis-7-[(Methylthio)methoxy]-2,2,2,2-tetramethyl-4,4a-dihydro-spiro[1,3-dioxolane-4,6'-furo[3,2-d][1,3]dioxin]; 151252-16-3
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Quality Control

Our Spiro1,3-Dioxolane-4,6-6Hfuro3,2-D1,3Dioxin, 4,4A-Dihydro-2,2,2,2-Tetramethyl-7-(Methylthio)Methoxy-, (4As-Cis)- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for stereochemical integrity, and NMR/IR for structural confirmation, to ensure it meets the exacting standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be sensitive to moisture and prolonged exposure to air; therefore, containers should be kept tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.