Description

Tenivastatin Calcium is a synthetic, selective HMG-CoA reductase inhibitor belonging to the statin class of pharmaceuticals. This active pharmaceutical ingredient (API) is critical for the development of cholesterol-lowering medications that help manage hyperlipidemia and reduce cardiovascular risk. It is primarily utilized by pharmaceutical manufacturers and research institutions engaged in the formulation of solid oral dosage forms, such as tablets and capsules, for the global healthcare market.

Application

• Pharmaceutical API: Primary use as the active ingredient in prescription medications for lowering LDL (bad) cholesterol and triglyceride levels.
• Cardiovascular Drug Formulation: Formulation into tablets, capsules, and other solid oral dosage forms for the treatment of hypercholesterolemia and dyslipidemia.
• Generic Drug Manufacturing: Sourcing for the production of generic (non-proprietary) versions of tenivastatin-based therapies.
• Clinical Research & Development: Use in preclinical and clinical studies for evaluating new cardiovascular treatment regimens or combination therapies.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in pharmaceutical laboratories.

Basic Information

Product Name	Tenivastatin Calcium
CAS No.	151006-18-7
Molecular Formula	C25H37F2NO6•1/2Ca
Molecular Weight	506.57 g/mol (Free acid: 485.57)
Synonyms	Tenivastatin Calcium Salt; (3R,5S)-7-[2-Cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]-3,5-dihydroxyhept-6-enoic Acid Calcium Salt; Tenivastatin Ca; Tenivastatin Hemicalcium Salt; SQ-33600; SQ 33600; SQ33600; Livalo® (brand name for Pitavastatin, a related statin - often referenced in searches)
EINECS	Contact for details

Quality Control

Our Tenivastatin Calcium is manufactured under strict quality management systems. Each batch is tested to ensure it meets high-purity standards suitable for pharmaceutical use, with typical purity levels exceeding 98.5%. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing results for assay, related substances, residual solvents, and microbiological limits. We support compliance with ICH Q7 guidelines and relevant pharmacopeial standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.5% - 101.0% (on anhydrous basis)
Related Substances (HPLC)	Total impurities ≤ 1.0% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Complies with ICH Q3C
Heavy Metals	≤ 20 ppm
Microbiological Enumeration	Total aerobic microbial count ≤ 1000 cfu/g Total combined yeasts/molds ≤ 100 cfu/g
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.