Description

L-Allothreonine,4-Fluoro-,Ethylester(9Ci) is a fluorinated amino acid ester derivative, a high-value building block in synthetic organic chemistry. This compound matters for its role as a key chiral intermediate in the development of novel pharmaceuticals and bioactive molecules, where the fluorine atom and specific stereochemistry are critical for modulating biological activity and metabolic stability. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and advanced material sectors engaged in peptide mimetic and drug discovery programs. CAS No. 150672-44-9.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of fluorinated peptide analogs, protease inhibitors, and other active pharmaceutical ingredients (APIs).
• Agrochemical Research: Used in developing novel herbicides or pesticides where the fluorine moiety enhances lipophilicity and target binding.
• Biochemical Tool: Serves as a substrate or inhibitor in enzymatic studies to investigate fluorine's effect on protein-ligand interactions.
• Peptide Chemistry: Incorporated into custom peptides to study structure-activity relationships (SAR) and improve metabolic stability.
• Material Science: Potential monomer for creating specialized polymers with unique surface properties or biocompatibility.
• Diagnostic Agent Development: Used in research for synthesizing fluorinated tracers or contrast agents for imaging technologies like PET.

Basic Information

Product Name	L-Allothreonine,4-Fluoro-,Ethylester(9Ci)
CAS No.	150672-44-9
Molecular Formula	C7H12FNO3
Molecular Weight	177.17 g/mol
Synonyms	L-4-Fluoroallothreonine ethyl ester; Ethyl (2S,3S)-2-amino-3-fluoro-4-hydroxybutanoate; (2S,3S)-2-Amino-3-fluoro-4-hydroxybutyric acid ethyl ester; 4-Fluoro-L-allothreonine ethyl ester; L-Allothreonine, 4-fluoro-, ethyl ester; Ethyl L-4-fluoroallothreoninate; 9CI: L-Allothreonine,4-Fluoro-,Ethylester; Fluorinated threonine derivative ethyl ester
EINECS	Contact for details

Quality Control

Our L-Allothreonine,4-Fluoro-,Ethylester(9Ci) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a desiccated environment to prevent degradation. For long-term storage, consider inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.