Description

Methyl 2,3,4-Tri-o-Isobutyryl-1-o-Trichloroacetimidoyl-A-D-Glucopyranuronate is a sophisticated, high-purity carbohydrate derivative and a key protected intermediate in synthetic organic chemistry. Its value lies in enabling precise glycosylation reactions, which are fundamental for constructing complex oligosaccharides and glycoconjugates. This compound is essential for researchers and manufacturers in the pharmaceutical industry, particularly in the development of novel therapeutics, vaccines, and diagnostic agents where specific sugar moieties are required.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of complex carbohydrate-based active pharmaceutical ingredients (APIs) and prodrugs.
• Glycobiology Research: Used in academic and industrial laboratories to study glycosylation processes and synthesize specific oligosaccharide structures.
• Glycoconjugate Vaccine Development: Serves as a key precursor for attaching carbohydrate antigens to carrier proteins, a core technology in modern vaccine design.
• Synthesis of Heparin Mimetics: Employed in the production of synthetic heparin-like compounds for anticoagulant research and development.
• Production of Diagnostic Reagents: Utilized to create labeled sugars or probes for diagnostic assays and imaging.
• Process Development & Scale-up: Supports process chemistry teams in optimizing synthetic routes for carbohydrate-based molecules from lab to pilot scale.

Basic Information

Item	Details
Product Name	Methyl 2,3,4-Tri-o-Isobutyryl-1-o-Trichloroacetimidoyl-A-D-Glucopyranuronate
CAS No.	150607-96-8
Molecular Formula	C22H30Cl3NO10
Molecular Weight	575.83 g/mol
Synonyms	Methyl 2,3,4-Tri-O-isobutyryl-1-O-(trichloroacetimidoyl)-α-D-glucopyranuronate; Methyl (2,3,4-Tri-O-isobutyryl-α-D-glucopyranosyluronate) trichloroacetimidate; 1-O-(Trichloroacetimidoyl)-2,3,4-tri-O-isobutyryl-α-D-glucopyranuronic acid methyl ester; α-D-Glucopyranuronic acid, methyl ester, 2,3,4-triisobutyrate, 1-(trichloroacetimidate); Trichloroacetimidate Glucuronate Donor; Protected Glucuronic Acid Trichloroacetimidate
EINECS	Contact for details

Quality Control

Every batch of Methyl 2,3,4-Tri-o-Isobutyryl-1-o-Trichloroacetimidoyl-A-D-Glucopyranuronate is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure identity, purity, and consistency for your critical synthetic applications. A detailed Certificate of Analysis (COA) including results from HPLC, NMR, and other relevant tests is supplied with each shipment to guarantee compliance with your research or cGMP guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and reactivity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.