Description

4-Amino-D-Phenylalanine Methyl Ester is a chiral, non-natural amino acid derivative of significant importance in advanced organic synthesis. This compound serves as a critical chiral building block and intermediate for the development of pharmaceuticals, bioactive peptides, and complex organic molecules. It is particularly valuable for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require high-purity, enantiomerically pure intermediates for drug discovery and process development.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of novel active pharmaceutical ingredients (APIs), especially in oncology and neurology research.
• Peptide Synthesis: Used as a protected D-amino acid derivative in solid-phase and solution-phase peptide synthesis to incorporate specific chirality and functionality.
• Protease Inhibitor Development: Serves as a core structural component in the design and synthesis of enzyme inhibitors targeting various proteases.
• Chemical Biology & Proteomics: Employed in the creation of activity-based probes and labeled compounds for studying enzyme function and protein interactions.
• Asymmetric Catalysis Ligand Precursor: Utilized in the preparation of chiral ligands and catalysts for asymmetric synthesis applications.
• Fine Chemical Manufacturing: Acts as a specialized intermediate for producing high-value, complex organic compounds with specific stereochemical requirements.

Basic Information

Product Name	4-Amino-D-Phenylalanine Methyl Ester
CAS No.	150570-99-3
Molecular Formula	C10H14N2O2
Molecular Weight	194.23 g/mol
Synonyms	D-4-Aminophenylalanine Methyl Ester; Methyl (2R)-2-amino-3-(4-aminophenyl)propanoate; (R)-Methyl 2-amino-3-(4-aminophenyl)propanoate; D-Phenylalanine, 4-amino-, methyl ester; Methyl D-4-aminophenylalaninate; 4-Amino-D-Phe-OMe; (R)-2-Amino-3-(4-aminophenyl)propionic acid methyl ester
EINECS	Contact for details

Quality Control

Our 4-Amino-D-Phenylalanine Methyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for research and pharmaceutical applications. A Certificate of Analysis (COA) detailing identity, purity (typically ≥98%), enantiomeric excess, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.