Description

5-(tert-Butyl) 1-Ethyl 5-Azaspiro[2.4]Heptane-1,5-Dicarboxylate is a high-value, synthetically versatile spirocyclic building block. This compound is a key protected intermediate in the synthesis of complex pharmaceutical molecules, particularly those targeting the central nervous system. It is primarily utilized by research and development teams, process chemists, and manufacturers in the pharmaceutical and agrochemical industries for constructing novel molecular scaffolds.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for neurological and psychiatric disorders.
• Medicinal Chemistry Research: Used as a constrained scaffold in drug discovery programs to explore new chemical space and improve drug-like properties.
• Agrochemical Synthesis: Serves as a building block for developing novel crop protection agents and pesticides with unique modes of action.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Process Chemistry Development: Used for scaling up synthetic routes and optimizing manufacturing processes for commercial production.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects requiring specialized spirocyclic architectures.

Basic Information

Product Name	5-(tert-Butyl) 1-Ethyl 5-Azaspiro[2.4]Heptane-1,5-Dicarboxylate
CAS No.	150543-45-6
Molecular Formula	C14H23NO4
Molecular Weight	269.34 g/mol
Synonyms	1-Ethyl 5-(tert-butyl) 5-azaspiro[2.4]heptane-1,5-dicarboxylate; 5-Azaspiro[2.4]heptane-1,5-dicarboxylic acid, 1-ethyl 5-(1,1-dimethylethyl) ester; tert-Butyl 1-ethoxycarbonyl-5-azaspiro[2.4]heptane-5-carboxylate; 5-(tert-Butoxycarbonyl)-1-(ethoxycarbonyl)-5-azaspiro[2.4]heptane; BOC-Azaspiroheptane-1-ethyl ester; Azaspiro[2.4]heptane dicarboxylate derivative
EINECS	Contact for details

Quality Control

Our 5-(tert-Butyl) 1-Ethyl 5-Azaspiro[2.4]Heptane-1,5-Dicarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency suitable for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to prevent moisture absorption and contamination. Handle and store in accordance with good laboratory and manufacturing practices.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.