Description

5-Azaspiro[2.4]Heptan-1-Amine Dihydrochloride is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic amine structure. This compound is of significant value for medicinal chemistry research and development, serving as a critical building block for synthesizing novel active pharmaceutical ingredients (APIs). It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries. The compound, CAS 150543-40-1, is supplied to meet the stringent requirements of modern drug discovery programs.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates targeting central nervous system (CNS) disorders, pain management, and other therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its constrained spirocyclic scaffold.
• Process Chemistry Development: Serves as a starting material or intermediate in the scale-up and optimization of API synthesis routes under GMP conditions.
• Chemical Biology Probes: Utilized in the development of tool compounds and probes for investigating biological pathways and target validation.
• Custom Synthesis: Foundation for the custom manufacturing of specialized amines and complex molecular architectures for client-specific projects.

Basic Information

Product Name	5-Azaspiro[2.4]Heptan-1-Amine Dihydrochloride
CAS No.	150543-40-1
Molecular Formula	C6H12N2·2HCl
Molecular Weight	197.09 g/mol
Synonyms	1-Amino-5-azaspiro[2.4]heptane dihydrochloride; 5-Azaspiro[2.4]heptan-1-amine, hydrochloride (1:2); 5-Azaspiro[2.4]heptan-1-amine, dihydrochloride; 1-Amino-5-azaspiro[2.4]heptane hydrochloride; Spiro[2.4]heptan-1-amine, 5-aza-, dihydrochloride; 150543-40-1; 5-Azaspiro[2.4]heptane-1-amine dihydrochloride
EINECS	Contact for details

Quality Control

Our 5-Azaspiro[2.4]Heptan-1-Amine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability, consistency, and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.