Description

Cimetropium CAS NO 150521-16-7 is a synthetic anticholinergic agent belonging to the quaternary ammonium class. This compound is valued for its potent and selective antagonistic activity at muscarinic receptors, making it a key intermediate in pharmaceutical research and development. It is primarily utilized by the pharmaceutical industry for the synthesis of active pharmaceutical ingredients (APIs) targeting gastrointestinal and genitourinary spasmodic disorders.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of antispasmodic and anticholinergic drug substances.
• Research & Development: Used in preclinical and clinical studies to investigate muscarinic receptor pharmacology and therapeutic applications.
• Active Pharmaceutical Ingredient (API) Synthesis: Employed in the manufacturing process of finished dosage forms for treating conditions like irritable bowel syndrome (IBS) and urinary incontinence.
• Reference Standard: Serves as a high-purity analytical standard for quality control and regulatory compliance testing in pharmaceutical laboratories.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	Cimetropium
CAS No.	150521-16-7
Molecular Formula	C21H30BrNO3
Molecular Weight	424.38 g/mol
Synonyms	Cimetropium Bromide; (3S)-3-[(2S)-2-Cyclopentyl-2-hydroxy-2-phenylacetoxy]-1,1-dimethylpyrrolidinium Bromide; 1-Methyl-3-[(2S)-2-cyclopentyl-2-hydroxy-2-phenylacetyloxy]-1-azoniabicyclo[2.2.2]octane Bromide; Cimetropium Bromide (USAN); UNII-2XG7T2T6SE; Alginor; CAS 150521-16-7
EINECS	Contact for details

Quality Control

Our Cimetropium is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling via advanced techniques like HPLC and NMR, to ensure it meets stringent pharmaceutical-grade specifications. Certificates of Analysis (COA) documenting full compliance with relevant standards are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.