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Dihydro Artemisinin Dimer CAS NO 150358-71-7


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CAS No.:150358-71-7

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Dihydro Artemisinin Dimer CAS NO 150358-71-7 is a synthetic derivative of artemisinin, representing a dimeric structure with enhanced chemical stability and potential for novel biological activity. This compound is of significant interest for advanced pharmaceutical research and development, particularly in exploring new therapeutic pathways. It is primarily sought by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in developing next-generation antimalarial agents or investigating its broader pharmacological applications.

Application

  • Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel artemisinin-based combination therapies (ACTs) and other investigational drugs.
  • Antimalarial Research: Used as a reference standard or active investigational compound in studies targeting *Plasmodium* species, including drug-resistant strains.
  • Medicinal Chemistry: Provides a core scaffold for structure-activity relationship (SAR) studies to optimize potency, bioavailability, and metabolic stability.
  • Anticancer Research: Investigated in preclinical studies for potential antiproliferative and apoptosis-inducing effects against various cancer cell lines.
  • Antiviral Agent Development: Explored for activity against a range of viral pathogens in early-stage research programs.
  • Biochemical Tool Compound: Utilized in mechanistic studies to understand cellular pathways and molecular targets affected by artemisinin derivatives.

Basic Information

Product Name Dihydro Artemisinin Dimer
CAS No. 150358-71-7
Molecular Formula C30H44O10
Molecular Weight 564.67 g/mol
Synonyms Dihydroartemisinin Dimer; Arteannuin B Dimer; Dihydroqinghaosu Dimer; DHA Dimer; (3R,5aS,6R,8aS,9R,10S,12R,12aR)-Decahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10(3H)-one, dimer; Artemisinin, dihydro-, dimer; NSC 369815
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Quality Control

Our Dihydro Artemisinin Dimer is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and residual solvent analysis. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with research-grade and cGMP standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. This material is light-sensitive and easily oxidized; prolonged exposure to air, light, or elevated temperatures should be avoided to maintain stability and purity.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to reference spectrum
Identification (HPLC) Retention time matches reference standard
Assay (HPLC) ≥ 98.0%
Related Substances (HPLC) Total impurities ≤ 2.0%
Single Maximum Impurity ≤ 0.5%
Loss on Drying ≤ 0.5%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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