Description

7-(5-Fluoropentyl)Estradiol is a synthetic, fluorinated derivative of the natural hormone estradiol, designed for advanced research and development applications. This compound is valued for its modified pharmacokinetic profile, offering researchers a tool to study hormone-receptor interactions with enhanced specificity and metabolic stability. It is primarily utilized by pharmaceutical R&D teams, academic institutions, and biotechnology companies engaged in endocrinology, oncology, and novel therapeutic agent development.

Application

• Pharmaceutical Research & Development: Serves as a key intermediate or reference standard in the synthesis and study of novel steroidal therapeutics.
• Endocrinology Studies: Used as a molecular probe to investigate estrogen receptor (ER) binding affinity, selectivity, and downstream signaling pathways.
• Oncology Research: Employed in preclinical studies targeting hormone-dependent cancers, such as certain breast and prostate cancers.
• Metabolic Stability Profiling: The fluoropentyl side chain makes it a candidate for studying the effects of fluorination on drug metabolism and half-life.
• Biochemical Assay Development: Acts as a ligand in the development and validation of competitive binding assays (e.g., ELISA, radioreceptor assays).
• Academic & Institutional Research: Provides a specialized chemical tool for graduate and post-doctoral research in medicinal chemistry and pharmacology.

Basic Information

Product Name	7-(5-Fluoropentyl)Estradiol
CAS No.	150187-33-0
Molecular Formula	C23H33FO2
Molecular Weight	360.51 g/mol
Synonyms	Estra-1,3,5(10)-triene-3,17β-diol, 7-(5-fluoropentyl)-; 7-(5-Fluoropentyl)-17β-estradiol; 7-Fluoropentylestradiol; 7-FPE2; 17β-Estradiol 7-(5-fluoropentyl) ether
EINECS	Contact for details

Quality Control

Every batch of 7-(5-Fluoropentyl)Estradiol is manufactured and analyzed under strict quality management protocols to ensure identity, purity, and consistency. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with research-grade standards. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. For long-term storage, consider storing under an inert atmosphere at -20°C to maximize stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 95.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.