Description

1,4-Dioxaspiro[4.5]Decane-7-Carboxylic Acid is a high-value spirocyclic carboxylic acid derivative, serving as a critical chiral building block and synthetic intermediate in advanced organic synthesis. Its unique fused ring structure provides a rigid scaffold that is essential for constructing complex molecules with precise stereochemistry. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug candidates, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Agrochemical Research: Used in the development of novel herbicides and pesticides, where its spirocyclic core contributes to biological activity.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands used in asymmetric catalysis, such as in hydrogenation or cross-coupling reactions.
• Material Science: A building block for specialty polymers and advanced organic materials requiring specific rigid, functionalized monomers.
• Academic & Process Chemistry: Employed in methodological studies and scale-up process development for complex organic molecule construction.

Basic Information

Product Name	1,4-Dioxaspiro[4.5]Decane-7-Carboxylic Acid
CAS No.	150013-85-7
Molecular Formula	C9H14O4
Molecular Weight	186.21 g/mol
Synonyms	7-Carboxy-1,4-dioxaspiro[4.5]decane; 1,4-Dioxaspiro[4.5]decane-7-carboxylic acid; Spiro[1,3-dioxolane-2,1'-cyclohexane]-4'-carboxylic acid; 4'-Carboxyspiro[1,3-dioxolane-2,1'-cyclohexane]; 7-Carboxy-1,4-dioxaspiro[4,5]decane
EINECS	Contact for details

Quality Control

Our production of 1,4-Dioxaspiro[4.5]Decane-7-Carboxylic Acid adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality system is designed to support cGMP compliance for pharmaceutical applications, and we are capable of meeting custom purity specifications (e.g., >98%, >99%) upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.