Description

Carbamic Acid, (2-Ethyl-1-Methyl-3-Butynyl)-, 1,1-Dimethylethyl Ester is a specialized chiral intermediate featuring a unique alkyne-substituted carbamate structure. This compound is valued for its role as a key building block in the synthesis of complex, biologically active molecules, offering precise stereochemical control. It is primarily required by research institutions and pharmaceutical development companies engaged in the creation of new therapeutic agents and advanced fine chemicals.

Application

• Pharmaceutical Intermediate: A critical chiral synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and antiviral therapies.
• Asymmetric Synthesis: Utilized in stereoselective reactions to construct complex molecular architectures with high enantiomeric purity.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Process Chemistry Development: Employed in scaling up synthetic routes from laboratory to pilot plant scale for potential commercial manufacturing.
• Fine Chemical Production: Used in the custom synthesis of advanced intermediates for agrochemicals and specialty materials.

Basic Information

Product Name	Carbamic Acid, (2-Ethyl-1-Methyl-3-Butynyl)-, 1,1-Dimethylethyl Ester
CAS No.	149837-05-8
Molecular Formula	C12H21NO2
Molecular Weight	211.30 g/mol
Synonyms	tert-Butyl N-[(2S)-1-ethyl-2-methylbut-3-yn-2-yl]carbamate; (S)-tert-Butyl (1-ethyl-2-methylbut-3-yn-2-yl)carbamate; (S)-N-(1-Ethyl-2-methyl-3-butyn-2-yl)carbamic Acid tert-Butyl Ester; (S)-N-Boc-1-ethyl-2-methyl-3-butyn-2-amine; (S)-Boc-AEMA; [S- CAS 149837-05-8; (2S)-2-[(tert-Butoxycarbonyl)amino]-2-methyl-3-pentyn
EINECS	Contact for details

Quality Control

Our production of this high-value intermediate adheres to strict quality management systems. Every batch is characterized and tested to ensure identity, purity, and chiral integrity, typically meeting a minimum purity of 97% (by HPLC) with high enantiomeric excess. A comprehensive Certificate of Analysis (COA) detailing specifications such as assay, chiral purity, and residual solvents is provided with each shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Enantiomeric Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.