Description

Lovastatin Dimer is a high-purity pharmaceutical intermediate and reference standard derived from the statin family of compounds. This dimeric form is of significant interest for advanced research and development in metabolic and cardiovascular pharmacology. It serves as a critical building block for scientists and manufacturers in the pharmaceutical and fine chemical industries, particularly those focused on developing or analyzing cholesterol-lowering agents and their related metabolites.

Application

• Pharmaceutical Reference Standard: Used for the qualitative and quantitative analysis of lovastatin and its derivatives in drug substances and finished products via HPLC, LC-MS, or other analytical methods.
• Metabolic Pathway Research: A key compound for studying the biotransformation, pharmacokinetics, and metabolic pathways of statin drugs in preclinical and clinical research.
• Process Impurity Profiling: Employed in the identification and control of dimeric impurities during the synthesis and purification of lovastatin (CAS 75330-75-5) and related statin APIs.
• Advanced Synthetic Intermediate: Serves as a specialized precursor in the research-scale synthesis of novel statin analogs or for structure-activity relationship (SAR) studies.
• Quality Control & Method Development: Essential for developing, validating, and calibrating analytical methods in pharmaceutical QC/QA laboratories to ensure product purity and regulatory compliance.

Basic Information

Product Name	Lovastatin Dimer
CAS No.	149756-62-7
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Lovastatin Dimer; Dimeric Lovastatin; (3R,5R)-7-[(1S,2S,6R,8S,8aR)-8-{2-[(2S,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl]ethyl}-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]-3,5-dihydroxyheptanoic acid dimer; Statin Dimer Impurity; Mevinolin Dimer
EINECS	Contact for details

Quality Control

Our Lovastatin Dimer is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatographic purity assays and structural confirmation, to ensure it meets the high standards required for research and pharmaceutical development. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and related substances is provided with every shipment to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Individual impurity ≤ 2.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.