Description

Lucifer Yellow Cadaverine is a highly fluorescent, membrane-impermeant bioconjugate dye widely used as a vital tracer in cell biology and neuroscience. Its core value lies in its ability to form stable conjugates with proteins and other biomolecules, enabling precise tracking and visualization within living systems. This product is essential for researchers and industrial scientists in neuroscience, cell biology, and diagnostic assay development, particularly for neuronal tracing, endocytosis studies, and as a fluorescent label for antibodies and other probes.

Application

• Neuronal Tracing and Circuit Mapping: As a classic fluorescent tracer for microinjection into single neurons to visualize morphology and synaptic connections.
• Endocytosis and Vesicle Trafficking Studies: Used to label fluid-phase markers and track internalization pathways within cells.
• Bioconjugation and Probe Labeling: Conjugation to dextrans, proteins, or antibodies to create custom fluorescent probes for imaging and flow cytometry.
• Gap Junction Communication Assays: Utilized in scrape-loading/dye transfer experiments to assess intercellular communication.
• Fixed-Tissue Histology: Acts as a counterstain or specific label in fixed tissue sections following conjugation to targeting molecules.
• Model System Research: Applied in developmental biology using organisms like C. elegans or Drosophila for lineage tracing.

Basic Information

Product Name	Lucifer Yellow Cadaverine
CAS No.	149733-79-9
Molecular Formula	C₂₆H₂₉N₅O₉S₂
Molecular Weight	627.67 g/mol
Synonyms	Lucifer Yellow CH; Lucifer Yellow CH Cadaverine; LY Cadaverine; 6-Amino-2-[[5-[[(5-amino-1-oxopentyl)amino]carbonyl]-2-hydroxyphenyl]azo]-1,3-benzenedisulfonic acid; 4-Amino-6-[[5-[[(5-aminopentyl)amino]carbonyl]-2-hydroxyphenyl]azo]-1,3-benzenedisulfonic acid; Lucifer Yellow Carboxylic Acid Cadaverine; LYC; LY-CH
EINECS	Contact for details

Quality Control

Our Lucifer Yellow Cadaverine is produced under stringent conditions to ensure high batch-to-batch consistency and performance in sensitive biological applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity, spectrophotometry for absorbance/fluorescence verification, and functional testing in tracer applications. Certificates of Analysis (COA) detailing purity, identity, and performance characteristics are available upon request to support your research and quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This compound is hygroscopic (moisture-sensitive) and light-sensitive. For long-term storage, desiccate and keep under inert atmosphere if possible. Allow the vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	Yellow to orange-yellow powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Absorbance (Max)	428 - 432 nm (in water)
Fluorescence (Max)	535 - 540 nm (in water)
Water Content (KF)	≤ 5.0 %
Solubility	Soluble in water, DMSO
Functional Test	Suitable for neuronal tracing

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.