Description

(2S)-2-Amino-3-{1H-Pyrrolo[3,2-C]Pyridin-3-Yl}Propanoic Acid is a high-purity, non-proteinogenic amino acid derivative featuring a fused pyrrolopyridine heterocyclic system. This compound is of significant interest for its role as a sophisticated building block in pharmaceutical research and development. It is primarily utilized by medicinal chemists and process development scientists in the life sciences sector for the synthesis of novel therapeutic agents, particularly in oncology and central nervous system (CNS) drug discovery.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and synthesis of novel small-molecule drug candidates.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its unique fused heterocyclic scaffold.
• Proteolysis-Targeting Chimera (PROTAC) Development: Serves as a potential linker or warhead component in the design of targeted protein degradation therapeutics.
• Peptidomimetic Design: Incorporated into peptide analogs to enhance metabolic stability, bioavailability, and binding affinity.
• Bioconjugation: Utilized for the site-specific modification of proteins, antibodies, or other biomolecules in biopharmaceutical development.
• Chemical Biology Probes: Acts as a key component in the development of tool compounds for investigating biological pathways and target validation.

Basic Information

Product Name	(2S)-2-Amino-3-{1H-Pyrrolo[3,2-C]Pyridin-3-Yl}Propanoic Acid
CAS No.	149704-62-1
Molecular Formula	C10H11N3O2
Molecular Weight	205.21 g/mol
Synonyms	(2S)-2-Amino-3-(1H-pyrrolo[3,2-c]pyridin-3-yl)propanoic acid; 3-(1H-Pyrrolo[3,2-c]pyridin-3-yl)-L-alanine; L-3-(1H-Pyrrolo[3,2-c]pyridin-3-yl)alanine; 1H-Pyrrolo[3,2-c]pyridine-3-propanoic acid, α-amino-, (αS)-; 149704-62-1; UNII-9V7I2C4Y8H; 9V7I2C4Y8H; L-Pyrrolo[3,2-c]pyridinylalanine
EINECS	Contact for details

Quality Control

Our (2S)-2-Amino-3-{1H-Pyrrolo[3,2-C]Pyridin-3-Yl}Propanoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and comprehensive spectroscopic identification (NMR, MS). Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client requirements for research or cGMP applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a desiccated environment and handled under conditions that minimize exposure to ambient light and humidity to ensure long-term stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.