Description

Carbamic Acid, [(1S)-2-(Hydroxyimino)-1-Methylethyl]-, 1,1-Dimethylethyl Ester is a specialized chiral building block and intermediate of significant interest in advanced organic synthesis. This compound matters for its role in constructing complex molecules with precise stereochemistry, which is critical for developing bioactive compounds. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and other fine chemicals where stereochemical control is paramount.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for drugs targeting neurological or metabolic pathways.
• Agrochemical Synthesis: Used in the production of advanced, stereospecific pesticides and herbicides where biological activity is enantiomer-dependent.
• Asymmetric Synthesis: Serves as a versatile building block in academic and industrial research for constructing complex molecules with defined stereocenters via reactions like nucleophilic additions or cyclizations.
• Peptidomimetic Research: Employed in the design and synthesis of peptide analogs and enzyme inhibitors due to its carbamate and oxime functional groups.
• Chemical Biology Probes: Utilized in the creation of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis Services: A critical starting material for contract research and manufacturing organizations (CROs/CMOs) offering bespoke chemical synthesis.

Basic Information

Product Name	Carbamic Acid, [(1S)-2-(Hydroxyimino)-1-Methylethyl]-, 1,1-Dimethylethyl Ester
CAS No.	149609-81-4
Molecular Formula	C9H18N2O3
Molecular Weight	202.25 g/mol
Synonyms	(S)-tert-Butyl (1-(hydroxyimino)propan-2-yl)carbamate; (S)-tert-Butyl (2-(hydroxyimino)-1-methylethyl)carbamate; (1S)-2-(Hydroxyimino)-1-methylethyl-carbamic acid tert-butyl ester; tert-Butyl N-[(1S)-2-(hydroxyimino)-1-methylethyl]carbamate; (S)-tert-Butyl (1-(hydroxyimino)-2-propyl)carbamate; (S)-O-tert-Butyl-N-(1-(hydroxyimino)propan-2-yl)carbamate; Boc-L-Alanin oxime; Contact for details on additional trade names.
EINECS	Contact for details

Quality Control

Our Carbamic Acid, [(1S)-2-(Hydroxyimino)-1-Methylethyl]-, 1,1-Dimethylethyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are available upon request. We support compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.