Description

(S)-(-)-1-(4-Bromophenyl)Ethyl Isocyanate is a high-purity, chiral organic intermediate of significant importance in asymmetric synthesis. Its value lies in its role as a key building block for introducing a specific stereochemistry and functional group into more complex molecules. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of enantiomerically pure drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the development of chiral pesticides and herbicides where specific stereochemistry is required for optimal biological activity and environmental safety.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric catalytic reactions.
• Advanced Material Research: Employed in the synthesis of specialty polymers and liquid crystals with tailored optical or mechanical properties.
• Custom Synthesis and Contract Manufacturing: A valuable starting material for custom chemical synthesis services targeting niche and high-value applications.

Basic Information

Product Name	(S)-(-)-1-(4-Bromophenyl)Ethyl Isocyanate
CAS No.	149552-52-3
Molecular Formula	C9H8BrNO
Molecular Weight	226.07 g/mol
Synonyms	(S)-1-(4-Bromophenyl)ethyl isocyanate; (S)-α-Methyl-4-bromobenzyl isocyanate; (-)-1-(4-Bromophenyl)ethyl isocyanate; (S)-(-)-1-(p-Bromophenyl)ethyl isocyanate; (S)-1-(4-Bromophenyl)ethan-1-yl isocyanate; p-Bromo-α-methylbenzyl isocyanate (S-enantiomer); (S)-1-(4-Bromophenyl)ethyl isocyanat
EINECS	Contact for details

Quality Control

Our production of (S)-(-)-1-(4-Bromophenyl)Ethyl Isocyanate adheres to stringent quality protocols to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is characterized by advanced analytical techniques including chiral HPLC, NMR, and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, enantiomeric excess (ee), and impurity profile is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a recommended temperature of 2-8°C under an inert atmosphere (e.g., nitrogen or argon) due to its moisture-sensitive and light-sensitive nature. Keep away from heat, open flames, and sources of ignition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Water Content (Karl Fischer)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.