Description

Ethyl 2-Cyano-3-[4-(Trifluoromethyl)Phenyl]Acrylate is a versatile and high-value acrylate ester derivative, serving as a critical building block and intermediate in advanced organic synthesis. Its molecular structure, featuring both a cyano and a trifluoromethylphenyl group, makes it an essential precursor for creating compounds with specific electronic and steric properties. This product is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and functional materials industries.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a trifluoromethyl moiety for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the acrylate scaffold contributes to biological activity.
• Organic Electronic Materials: Serves as a monomer or intermediate in the production of advanced polymers and small molecules for organic light-emitting diodes (OLEDs) and semiconductor applications.
• Dye and Pigment Manufacturing: Acts as a core structure for synthesizing specialized dyes and pigments, leveraging its conjugated system.
• Cross-coupling Reactions: A valuable substrate in palladium-catalyzed cross-coupling reactions (e.g., Heck, Suzuki) to construct complex biaryl systems.
• Chemical Research & Development: Employed in academic and industrial labs for exploring new synthetic methodologies and creating compound libraries for screening.

Basic Information

Product Name	Ethyl 2-Cyano-3-[4-(Trifluoromethyl)Phenyl]Acrylate
CAS No.	149550-21-0
Molecular Formula	C₁₃H₁₀F₃NO₂
Molecular Weight	269.22 g/mol
Synonyms	Ethyl (2E)-2-Cyano-3-[4-(trifluoromethyl)phenyl]prop-2-enoate; (E)-Ethyl 2-Cyano-3-(4-(trifluoromethyl)phenyl)acrylate; 2-Propenoic acid, 2-cyano-3-[4-(trifluoromethyl)phenyl]-, ethyl ester; Ethyl α-Cyano-β-(4-trifluoromethylphenyl)acrylate; Ethyl (E)-2-Cyano-3-(4-trifluoromethylphenyl)acrylate; Acrylic acid, 2-cyano-3-(4-trifluoromethylphenyl)-, ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 2-Cyano-3-[4-(Trifluoromethyl)Phenyl]Acrylate is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing batch-specific results are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.