Description

2,1',3',4',6'-Penta-o-Acetylsucrose is a key, fully acetylated derivative of sucrose, serving as a crucial synthetic intermediate in advanced carbohydrate chemistry. Its value lies in providing a protected scaffold for the selective synthesis of complex, high-value sucralose derivatives and other non-caloric sweeteners. This compound is essential for research and development laboratories, pharmaceutical intermediates manufacturers, and specialty chemical producers focused on sweetener innovation and carbohydrate-based drug discovery.

Application

• Key Intermediate for Sucralose Synthesis: Acts as a protected precursor in the multi-step industrial production of the high-intensity sweetener sucralose (Splenda®).
• Pharmaceutical Intermediate: Used in the research and development of novel carbohydrate-based pharmaceuticals and prodrugs, leveraging its reactive acetyl groups.
• Organic Synthesis Building Block: Serves as a versatile chiral starting material for synthesizing complex oligosaccharides and glycoconjugates in academic and industrial R&D.
• Flavor & Fragrance Industry: Employed in the synthesis of specialized sweetening agents and flavor modifiers for food and beverage applications.
• Biochemical Research: Utilized in enzymatic and chemical studies of glycosylation reactions and carbohydrate metabolism.
• Material Science: Investigated as a monomer or precursor for biodegradable polymers and specialty materials derived from renewable resources.

Basic Information

Product Name	2,1',3',4',6'-Penta-o-Acetylsucrose
CAS No.	149057-51-2
Molecular Formula	C22H30O16
Molecular Weight	550.46 g/mol
Synonyms	Sucrose Pentaacetate; 2,1',3',4',6'-Pentaacetyl Sucrose; 1,3,4,6-Tetra-O-acetyl-2-O-(2,3,4,6-tetra-O-acetyl-α-D-glucopyranosyl)-β-D-fructofuranose; Pentaacetyl Sucrose; Sucralose Intermediate; 2,1',3',4',6'-Penta-O-acetyl-D-sucrose; 2,1',3',4',6'-Penta-O-acetylsaccharose
EINECS	Contact for details

Quality Control

Our 2,1',3',4',6'-Penta-o-Acetylsucrose is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for synthetic intermediates. Certificates of Analysis (COA) detailing purity, residual solvents, and other critical parameters are provided with every shipment to guarantee traceability and consistency for your processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent absorption of atmospheric moisture, which can affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.