Description

4,5-Benzo-5'-(Iodoacetaminomethyl)-1',3,3,3',3'-Pentamethyl-1-(4-Sulfobutyl) Indodicarbocyanine is a specialized, high-purity cyanine dye derivative engineered for advanced research and diagnostic applications. This compound matters for its unique combination of a reactive iodoacetamide group and a sulfobutyl chain, enabling site-specific labeling and enhanced aqueous solubility. It is primarily needed by researchers and manufacturers in the fields of bioconjugation, fluorescence labeling, and bioimaging, particularly for developing sensitive probes and assays.

Application

• Bioconjugation and Protein Labeling: The reactive iodoacetaminomethyl group selectively binds to thiol groups (cysteine residues) in proteins, antibodies, and peptides for creating stable fluorescent conjugates.
• Fluorescent Probe Synthesis: Serves as a key intermediate or final dye for constructing NIR (Near-Infrared) fluorescent probes and sensors used in molecular biology.
• Bioimaging and Diagnostics: Used in the development of contrast agents and staining reagents for in vitro and in vivo imaging applications, including fluorescence microscopy and flow cytometry.
• Pharmaceutical Research: Employed in drug discovery for tracking drug distribution, studying pharmacokinetics, and developing targeted therapeutic agents.
• Material Science: Can be incorporated into polymers or nanoparticles to create functional materials with specific optical properties.

Basic Information

Item	Details
Product Name	4,5-Benzo-5'-(Iodoacetaminomethyl)-1',3,3,3',3'-Pentamethyl-1-(4-Sulfobutyl) Indodicarbocyanine
CAS No.	149021-66-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Cy7 Iodoacetamide; Sulfo-Cy7 Iodoacetamide; 1-(4-Sulfobutyl)-4,5-benzo-5'-(iodoacetaminomethyl)-1',3,3,3',3'-pentamethylindodicarbocyanine; Indodicarbocyanine, 4,5-benzo-5'-(iodoacetaminomethyl)-1',3,3,3',3'-pentamethyl-1-(4-sulfobutyl)-; Cy7 maleimide derivative; Near-IR reactive dye; Sulfonated Cy7 IAA
EINECS	Contact for details

Quality Control

Our 4,5-Benzo-5'-(Iodoacetaminomethyl)-1',3,3,3',3'-Pentamethyl-1-(4-Sulfobutyl) Indodicarbocyanine is produced under strict quality management protocols to ensure batch-to-batch consistency and high performance. Each lot undergoes rigorous analytical testing, including HPLC for purity and spectroscopic verification. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your research and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as indicated on the label or COA. This product is hygroscopic (moisture-sensitive) and light-sensitive; desiccants are recommended for long-term storage. Keep container tightly sealed when not in use to minimize exposure to air and moisture.

Specification

Item	Specification
Appearance	Dark green to blue-black solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content	≤ 2.0%
Solubility	Soluble in water, DMSO, DMF
Extinction Coefficient	Contact for details
Fluorescence Emission	~770 nm (in aqueous buffer)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.