Description

Carbamic Acid, [(2S)-2,3-Dihydroxypropyl]-, 1,1-Dimethylethyl Ester (9Ci) is a chiral, protected amino alcohol derivative of significant interest in advanced organic synthesis. This compound matters as a versatile and critical building block for constructing complex molecules with high stereochemical fidelity. Pharmaceutical, agrochemical, and fine chemical research and development teams need it for the production of active pharmaceutical ingredients (APIs), chiral ligands, and specialty polymers. Its protected diol and carbamate functionalities offer precise control in multi-step synthetic pathways.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of protease inhibitors, antiviral agents, and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the development of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Chiral Ligand & Catalyst Preparation: Serves as a precursor for ligands used in asymmetric catalysis, such as hydrogenation and oxidation reactions.
• Peptidomimetics & Bio-conjugates: Employed in the construction of peptide analogs and drug delivery conjugates due to its functional handle.
• Polymer Chemistry: Acts as a monomer or chain extender for synthesizing specialty polyurethanes and functional polymers with tailored properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms and cellular processes.

Basic Information

Product Name	Carbamic Acid, [(2S)-2,3-Dihydroxypropyl]-, 1,1-Dimethylethyl Ester (9Ci)
CAS No.	148983-25-9
Molecular Formula	C9H19NO4
Molecular Weight	205.25 g/mol
Synonyms	(2S)-3-[(tert-Butoxycarbonyl)amino]-1,2-propanediol; (S)-3-[(Boc)amino]-1,2-propanediol; (S)-3-(Boc-amino)-1,2-propanediol; Boc-DL-Serinol; tert-Butyl N-[(2S)-2,3-dihydroxypropyl]carbamate; (S)-1-Amino-3-(tert-butoxycarbonylamino)-2-propanol; N-Boc-L-serinol; N-(tert-Butoxycarbonyl)-L-serinol
EINECS	Contact for details

Quality Control

Our Carbamic Acid, [(2S)-2,3-Dihydroxypropyl]-, 1,1-Dimethylethyl Ester (9Ci) is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and cGMP manufacturing. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); containers must be kept tightly sealed to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.