Description

Boc-D-Phe-Pro-Osu is a high-purity, protected dipeptide building block widely used in solid-phase peptide synthesis (SPPS). This compound is critical for the efficient and controlled construction of complex peptide sequences, particularly those requiring the incorporation of D-phenylalanine and proline residues. It is an essential reagent for pharmaceutical R&D, biotechnology, and academic research focused on developing novel peptide-based therapeutics, diagnostics, and biochemical tools.

Application

• Pharmaceutical Peptide Synthesis: A key intermediate for the production of therapeutic peptides and peptidomimetics in drug discovery and development.
• Bioconjugation & Probe Development: Used to create labeled peptides for use as fluorescent probes, affinity tags, or diagnostic agents.
• Structure-Activity Relationship (SAR) Studies: Enables the systematic modification of peptide backbones to study biological activity and optimize drug candidates.
• Enzyme Substrate & Inhibitor Design: Serves as a building block for synthesizing specific substrates or inhibitors for proteases and other enzymes.
• Academic & Contract Research: A fundamental reagent in university and CRO laboratories for basic peptide chemistry research and custom synthesis services.
• Production of Peptide Fragments: Used in the segment condensation approach to assemble larger peptide chains and proteins.

Basic Information

Product Name	Boc-D-Phe-Pro-Osu
CAS No.	148980-30-7
Molecular Formula	C24H31N3O7
Molecular Weight	473.52 g/mol
Synonyms	Boc-D-Phenylalanyl-proline N-hydroxysuccinimide ester; N-(tert-Butoxycarbonyl)-D-phenylalanyl-L-proline N-succinimidyl ester; Boc-D-Phe-Pro-OSu; Boc-D-Phenylalanine-Proline-OSu ester; N-Boc-D-Phenylalanyl-L-proline Active Ester; N-Boc-D-Phe-Pro-OSu; tert-Butyloxycarbonyl-D-phenylalanyl-L-proline N-hydroxysuccinimide ester; (2,5-Dioxopyrrolidin-1-yl) (2S)-1-[(2R)-2-[(tert-butoxycarbonyl)amino]-3-phenylpropanoyl]pyrrolidine-2-carboxylate
EINECS	Contact for details

Quality Control

Our Boc-D-Phe-Pro-Osu is manufactured under strict quality management systems to ensure batch-to-batch consistency and high chemical purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and chiral purity, NMR for structural confirmation, and KF titration for moisture content. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% de
Water Content (KF)	≤ 1.0%
Solubility	Soluble in DMF, DMSO, acetonitrile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.