Description

Methyl4-Chloro-2-Fluorobenzoate is a high-purity organic intermediate of significant importance in advanced chemical synthesis. Its value lies in its role as a versatile building block for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for research and development chemists and production units requiring a reliable, high-quality precursor for active pharmaceutical ingredients (APIs) and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the fluorine and chlorine substituents contribute to biological activity.
• Liquid Crystal Material Precursor: Serves as a starting material for the synthesis of fluorinated liquid crystal compounds used in display technologies.
• Organic Light-Emitting Diode (OLED) Materials: Employed in the development of electron-transport or host materials for more efficient OLED devices.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D focused on fluorinated aromatic chemistry and cross-coupling reactions.
• Custom Synthesis: Provides a foundational structure for contract manufacturing organizations (CMOs) to produce bespoke fine chemicals for client-specific projects.

Basic Information

Product Name	Methyl 4-Chloro-2-Fluorobenzoate
CAS No.	148893-72-5
Molecular Formula	C8H6ClFO2
Molecular Weight	188.58 g/mol
Synonyms	Methyl 4-chloro-2-fluorobenzoate; 4-Chloro-2-fluorobenzoic acid methyl ester; Benzoic acid, 4-chloro-2-fluoro-, methyl ester; 2-Fluoro-4-chlorobenzoic acid methyl ester; Methyl 2-fluoro-4-chlorobenzoate; MFCD03094045
EINECS	Contact for details

Quality Control

Our Methyl 4-Chloro-2-Fluorobenzoate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency that meets the stringent requirements of pharmaceutical and fine chemical applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Melting Point	Contact for details
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.