Description

Pyrimidine,5-(Trimethylsilyl)-(9Ci) is a specialized organosilicon derivative of the pyrimidine heterocycle, characterized by the presence of a trimethylsilyl (TMS) protecting group. This compound is a valuable synthetic intermediate and protecting group reagent in advanced organic synthesis, particularly for nucleoside and nucleotide chemistry. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of active pharmaceutical ingredients (APIs), agrochemicals, and novel materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of modified nucleosides, nucleotides, and related antiviral or anticancer drug candidates.
• Agrochemical Research: Used in the development of novel herbicides and fungicides that target specific biochemical pathways.
• Material Science: Serves as a precursor for silicon-containing heterocyclic compounds used in advanced polymers and electronic materials.
• Organic Synthesis Reagent: Acts as a versatile protecting group for hydroxyl or amino functions in multi-step synthetic routes, facilitating selective reactions.
• Chemical Biology Probes: Utilized in the creation of labeled or modified biomolecules for mechanistic studies and diagnostic applications.

Basic Information

Product Name	Pyrimidine,5-(Trimethylsilyl)-(9Ci)
CAS No.	148854-13-1
Molecular Formula	C7H12N2Si
Molecular Weight	152.27 g/mol
Synonyms	5-(Trimethylsilyl)pyrimidine; 5-Trimethylsilylpyrimidine; Pyrimidine, 5-(trimethylsilyl)-; 5-TMS-Pyrimidine; 5-Pyrimidinyltrimethylsilane; Trimethyl(5-pyrimidinyl)silane; (Pyrimidin-5-yl)trimethylsilane
EINECS	Contact for details

Quality Control

Our Pyrimidine,5-(Trimethylsilyl)-(9Ci) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) for each lot, detailing key parameters such as assay, identity, and impurity profiles. Our quality management system is designed to meet the stringent requirements of research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.