Description

Cyclobutanecarboxylic Acid, 2,3-Bis(Methylene)-, Ethyl Ester, (R)- (9Ci) is a high-purity, chiral cyclobutane derivative of significant interest in advanced organic synthesis. This compound serves as a sophisticated building block for constructing complex molecular architectures with precise stereochemistry. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, particularly in programs targeting central nervous system (CNS) disorders or anti-infective agents.
• Agrochemical Synthesis: Used in the creation of novel, stereospecific pesticides and herbicides where the (R)-enantiomer imparts specific biological activity.
• Advanced Material Precursor: Serves as a monomer or cross-linking agent in the development of specialty polymers with unique thermal or mechanical properties.
• Ligand and Catalyst Development: Employed in the synthesis of chiral ligands for asymmetric catalysis, enhancing the efficiency of stereoselective transformations.
• Academic and Industrial R&D: A valuable tool for methodological studies in organic chemistry, enabling the exploration of new cyclobutane-based reactions and ring-strain chemistry.
• Flavor and Fragrance Chemistry: Potential use as an intermediate for synthesizing complex, naturally occurring odorants and flavor compounds with specific stereocenters.

Basic Information

Product Name	Cyclobutanecarboxylic Acid, 2,3-Bis(Methylene)-, Ethyl Ester, (R)- (9Ci)
CAS No.	148720-84-7
Molecular Formula	C10H14O2
Molecular Weight	166.22 g/mol
Synonyms	(R)-Ethyl 2,3-bis(methylene)cyclobutanecarboxylate; (R)-Ethyl 2,3-didehydrocyclobutanecarboxylate; Ethyl (R)-2,3-bis(methylene)cyclobutanecarboxylate; 2,3-Bis(methylene)cyclobutanecarboxylic acid ethyl ester, (R)-; Cyclobutanecarboxylic acid, 2,3-bis(methylene)-, ethyl ester, (R)-; (R)-2,3-Dimethylenecyclobutanecarboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our Cyclobutanecarboxylic Acid, 2,3-Bis(Methylene)-, Ethyl Ester, (R)- (9Ci) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing key parameters such as assay, enantiomeric excess (e.e.), and impurity profile. We adhere to cGMP standards where applicable, ensuring the material is suitable for demanding research and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider inert gas purging to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% e.e.
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.