Description

Ethyl 5-Cyanamide-4-(3,5-Dichlorophenyl)-4,5-Dihydro-1,3,4-Thiadiazole-2-Carboxylate is a high-purity, advanced pharmaceutical intermediate with the CAS number 148367-85-5. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex heterocyclic scaffolds. It is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical industries engaged in developing new drug candidates and crop protection agents.

Application

This specialized intermediate serves as a key precursor in several high-value synthetic pathways. Its primary and related applications include:

• Pharmaceutical Intermediate: Core building block for the research and development of new drug molecules, particularly those with thiadiazole-based structures.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, leveraging the bioactivity of the dichlorophenyl and thiadiazole moieties.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D focused on heterocyclic chemistry and medicinal chemistry.
• API Manufacturing: Employed in the scaled-up synthesis of potential active pharmaceutical ingredients under controlled GMP-like conditions.

Basic Information

Product Name	Ethyl 5-Cyanamide-4-(3,5-Dichlorophenyl)-4,5-Dihydro-1,3,4-Thiadiazole-2-Carboxylate
CAS No.	148367-85-5
Molecular Formula	C12H10Cl2N4O2S
Molecular Weight	345.20 g/mol
Synonyms	Ethyl 5-Carbamimidoyl-4-(3,5-dichlorophenyl)-4,5-dihydro-1,3,4-thiadiazole-2-carboxylate; 4,5-Dihydro-1,3,4-thiadiazole-2-carboxylic acid, 5-cyanoamino-4-(3,5-dichlorophenyl)-, ethyl ester; 5-Cyanamide-4-(3,5-dichlorophenyl)-4,5-dihydro-1,3,4-thiadiazole-2-carboxylic Acid Ethyl Ester; 148367-85-5; CAS 148367-85-5
EINECS	Contact for details

Quality Control

Our Ethyl 5-Cyanamide-4-(3,5-Dichlorophenyl)-4,5-Dihydro-1,3,4-Thiadiazole-2-Carboxylate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to relevant industry standards, and specifications can be tailored to meet specific research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.