Description

Diexo-3-tert-Butoxycarbonylamino-7-Oxa-Bicyclo[2.2.1]Hept-5-Ene-2-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate featuring a complex, functionalized bicyclic structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the fields of antiviral and anti-inflammatory drug development. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in process chemistry and the production of complex small-molecule therapeutics.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of complex drug molecules, particularly protease inhibitors and other biologically active compounds.
• Antiviral Drug Research: Used in the research and development of novel antiviral agents targeting specific viral enzymes.
• Anti-inflammatory Agent Synthesis: Serves as a precursor in the creation of new non-steroidal anti-inflammatory drugs (NSAIDs) with improved selectivity.
• Peptidomimetics: Integral to the construction of peptidomimetic scaffolds that mimic peptide structures for enhanced metabolic stability.
• Asymmetric Synthesis: Employed in asymmetric catalytic reactions and chiral pool synthesis due to its rigid, defined stereochemistry.
• Academic & Contract Research: A valuable reagent for academic research in organic methodology and for Contract Research Organizations (CROs) developing custom synthesis routes.

Basic Information

Product Name	Diexo-3-tert-Butoxycarbonylamino-7-Oxa-Bicyclo[2.2.1]Hept-5-Ene-2-Carboxylic Acid
CAS No.	148257-14-1
Molecular Formula	C₁₃H₁₉NO₅
Molecular Weight	269.29 g/mol
Synonyms	(1S,2R,3S,4R)-3-[(tert-Butoxycarbonyl)amino]-7-oxabicyclo[2.2.1]hept-5-ene-2-carboxylic acid; (1S,2R,3S,4R)-3-(Boc-amino)-7-oxabicyclo[2.2.1]hept-5-ene-2-carboxylic acid; 3-(Boc-amino)-7-oxabicyclo[2.2.1]hept-5-ene-2-carboxylic acid, exo-; Bicyclo[2.2.1]hept-5-ene-2-carboxylic acid, 3-[[(1,1-dimethylethoxy)carbonyl]amino]-7-oxa-, (1S,2R,3S,4R)-; 7-Oxabicyclo[2.2.1]hept-5-ene-2-carboxylic acid, 3-[(tert-butoxycarbonyl)amino]-, (1S,2R,3S,4R)-; Boc-7-oxanorbornene exo-amino acid; Contact for additional aliases.
EINECS	Contact for details

Quality Control

Our Diexo-3-tert-Butoxycarbonylamino-7-Oxa-Bicyclo[2.2.1]Hept-5-Ene-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and chiral purity analysis, to ensure it meets the high standards required for pharmaceutical R&D and cGMP manufacturing. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.