Description

Boc-3-Endo-Aminobicyclo[2.2.1]Hept-5-Ene-2-Endo-Carboxylic Acid is a high-purity, protected bicyclic amino acid derivative, serving as a critical chiral building block in advanced organic synthesis. Its value lies in its rigid, three-dimensional scaffold and orthogonal protecting groups, enabling the precise construction of complex molecular architectures. This compound is essential for researchers and process chemists in pharmaceutical development, agrochemical discovery, and materials science who require enantiomerically pure intermediates for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in neurology and antiviral research.
• Peptidomimetics & Constrained Peptides: Used to introduce conformational rigidity into peptide backbones, enhancing metabolic stability and biological activity.
• Agrochemical Synthesis: Employed in the development of enantiomerically pure herbicides and pesticides with improved efficacy and environmental profiles.
• Catalyst & Ligand Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Materials Science Research: A building block for specialty polymers and advanced organic materials with unique structural properties.
• Academic & R&D Laboratories: A valuable reagent for methodological studies in organic chemistry and the exploration of new synthetic pathways.

Basic Information

Item	Details
Product Name	Boc-3-Endo-Aminobicyclo[2.2.1]Hept-5-Ene-2-Endo-Carboxylic Acid
CAS No.	148257-12-9
Molecular Formula	C14H21NO4
Molecular Weight	267.32 g/mol
Synonyms	1,1-Dimethylethyl (1R,2S,3R,4S)-3-Amino-2,5-dihydro-1H-2,4-methano-1-benzazepine-1-carboxylate; tert-Butyl (1R,2S,3R,4S)-3-amino-2,5-dihydro-1H-2,4-methano-1-benzazepine-1-carboxylate; BOC-3-endo-Aminobicyclo[2.2.1]hept-5-ene-2-endo-carboxylic Acid; BOC-Protected 3-Aminonorbornene-2-carboxylic Acid; (1R,2S,3R,4S)-3-[(tert-Butoxycarbonyl)amino]bicyclo[2.2.1]hept-5-ene-2-carboxylic Acid
EINECS	Contact for details

Quality Control

Every batch of Boc-3-Endo-Aminobicyclo[2.2.1]Hept-5-Ene-2-Endo-Carboxylic Acid undergoes rigorous analytical testing to ensure it meets the stringent purity and chiral integrity standards required for advanced synthetic applications. Our quality assurance protocols are designed to support cGMP and ISO 9001 compliant workflows. A comprehensive Certificate of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under a dry inert atmosphere (e.g., nitrogen or argon) to prevent degradation. For long-term storage, desiccants are recommended.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.