Description

1,2,5-Oxadiazole-3-Carboxylic Acid, Methyl Ester (9Ci) is a specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key precursor in the development of novel pharmaceuticals and agrochemicals, particularly in constructing complex molecular frameworks. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a crucial synthon for the synthesis of novel drug candidates, particularly those containing the 1,2,5-oxadiazole (furazan) ring system, which is explored for various biological activities.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where the heterocyclic core can contribute to unique modes of action.
• Material Science Precursor: Acts as a building block for high-performance polymers, liquid crystals, and energetic materials due to its stable yet reactive heterocyclic structure.
• Chemical Biology Probe: Employed in the design and synthesis of molecular probes and tags for studying biological systems and enzyme mechanisms.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry and for exploring new chemical spaces in discovery research.

Basic Information

Product Name	1,2,5-Oxadiazole-3-Carboxylic Acid, Methyl Ester (9Ci)
CAS No.	148122-20-7
Molecular Formula	C4H4N2O3
Molecular Weight	128.09 g/mol
Synonyms	Methyl 1,2,5-oxadiazole-3-carboxylate; Methyl furazan-3-carboxylate; 3-Methoxycarbonyl-1,2,5-oxadiazole; Methyl 1,2,5-oxadiazole-3-carboxylic acid ester; Furazan-3-carboxylic acid methyl ester; 1,2,5-Oxadiazole-3-carboxylic acid, methyl ester; Methyl 3-furoate (ambiguous, verify context); 148122-20-7
EINECS	Contact for details

Quality Control

Our 1,2,5-Oxadiazole-3-Carboxylic Acid, Methyl Ester is produced and handled under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. The product is sensitive to strong alkali and should be kept away from incompatible materials. Recommended storage temperature is 2-8°C for long-term stability. Keep container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.