Description

1-Oxa-6-Azaspiro[2.5]Octane-6-Carboxylic Acid, 1,1-Dimethylethyl Ester is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic scaffold. This compound is of significant value in medicinal chemistry for constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the synthesis of innovative therapeutics, including central nervous system (CNS) agents and other bioactive molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates and novel active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new therapeutic agents.
• Protease Inhibitor Synthesis: Serves as a precursor in the construction of molecules targeting various protease enzymes.
• Chemical Biology Probes: Employed in the development of tool compounds for studying biological pathways and target validation.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke molecules for clinical trials.
• Academic Research: Utilized in university and institutional labs for methodological development and novel heterocyclic chemistry.

Basic Information

Product Name	1-Oxa-6-Azaspiro[2.5]Octane-6-Carboxylic Acid, 1,1-Dimethylethyl Ester
CAS No.	147804-30-6
Molecular Formula	C11H19NO3
Molecular Weight	213.27 g/mol
Synonyms	tert-Butyl 1-oxa-6-azaspiro[2.5]octane-6-carboxylate; 6-(tert-Butoxycarbonyl)-1-oxa-6-azaspiro[2.5]octane; 1-Oxa-6-azaspiro[2.5]octane-6-carboxylic acid tert-butyl ester; Boc-1-oxa-6-azaspiro[2.5]octane; Spiro[oxirane-2,1'-pyrrolidine]-1'-carboxylic acid, 1,1-dimethylethyl ester; 147804-30-6; tert-Butyl 1-oxa-6-azaspiro[2.5]octane-6-carboxylate
EINECS	Contact for details

Quality Control

Our 1-Oxa-6-Azaspiro[2.5]Octane-6-Carboxylic Acid, 1,1-Dimethylethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials. The container should be kept tightly sealed when not in use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.