Description

1,4-Dioxaspiro[4.5]Decan-8-Ylmethyl Methanesulfonate is a high-value, functionalized spirocyclic building block used in advanced organic synthesis. This compound is particularly significant for its role as a key intermediate in the development of complex pharmaceutical molecules and fine chemicals. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly those with spirocyclic or complex heterocyclic architectures.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides where specific stereochemistry and functional groups are required.
• Fine Chemical Production: Serves as a specialized precursor in the manufacture of dyes, flavors, fragrances, and other high-value specialty chemicals.
• Academic & Industrial Research: A valuable reagent for methodological development in organic chemistry, including studies on cyclization reactions and protecting group strategies.
• Material Science: Potential monomer or cross-linking agent in the development of polymers with unique thermal or mechanical properties.

Basic Information

Product Name	1,4-Dioxaspiro[4.5]Decan-8-Ylmethyl Methanesulfonate
CAS No.	147767-55-3
Molecular Formula	C11H20O5S
Molecular Weight	264.34 g/mol
Synonyms	8-(Methanesulfonyloxymethyl)-1,4-dioxaspiro[4.5]decane; 1,4-Dioxaspiro[4.5]decan-8-ylmethyl methanesulfonate; 8-(Methylsulfonyloxymethyl)-1,4-dioxaspiro[4.5]decane; Cyclohexanone ethylene ketal-8-methanol methanesulfonate; 8-(Hydroxymethyl)-1,4-dioxaspiro[4.5]decane methanesulfonate; Spirocyclic ketal mesylate; Cyclohexanone ketal mesylate derivative
EINECS	Contact for details

Quality Control

Our 1,4-Dioxaspiro[4.5]Decan-8-Ylmethyl Methanesulfonate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.