Description

7-Azaspiro[3.5]Nonane-7-Carboxylic Acid, 2-[[(1,1-Dimethylethoxy)Carbonyl]Amino]-, Phenylmethyl Ester is a sophisticated, high-purity chemical intermediate featuring a unique spirocyclic and protected amino acid structure. This compound is critical for enabling complex synthetic routes in modern pharmaceutical research and development, offering a versatile building block for constructing novel molecular architectures. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for the synthesis of active pharmaceutical ingredients (APIs) and other high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly those requiring spirocyclic or constrained peptide-like frameworks.
• Protease Inhibitor Research: Serves as a precursor or core structure in the development of novel protease inhibitors due to its peptide bond mimicry and protected amine functionality.
• Peptidomimetic Chemistry: Used to create peptidomimetics—molecules that mimic peptides—for drug discovery programs targeting various diseases.
• Agrochemical Synthesis: Employed in the research and development of new generation herbicides or fungicides with novel modes of action.
• Chemical Biology Probes: Utilized in the construction of specialized probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences industry.

Basic Information

Product Name	7-Azaspiro[3.5]Nonane-7-Carboxylic Acid, 2-[[(1,1-Dimethylethoxy)Carbonyl]Amino]-, Phenylmethyl Ester
CAS No.	147611-04-9
Molecular Formula	C20H28N2O4
Molecular Weight	360.45 g/mol
Synonyms	Benzyl 2-((tert-butoxycarbonyl)amino)-7-azaspiro[3.5]nonane-7-carboxylate; 2-(Boc-amino)-7-azaspiro[3.5]nonane-7-carboxylic acid benzyl ester; Boc-7-Azaspiro[3.5]nonane-7-COOBzl; 7-(Benzyloxycarbonyl)-2-((tert-butoxycarbonyl)amino)-7-azaspiro[3.5]nonane; N-Boc-7-Cbz-7-azaspiro[3.5]nonan-2-amine carboxylic acid derivative; tert-Butyl (7-(benzyloxycarbonyl)-7-azaspiro[3.5]nonan-2-yl)carbamate; (2-((tert-Butoxycarbonyl)amino)-7-azaspiro[3.5]nonan-7-yl)methyl benzoate (tautomeric form).
EINECS	Contact for details

Quality Control

Every batch of 7-Azaspiro[3.5]Nonane-7-Carboxylic Acid, 2-[[(1,1-Dimethylethoxy)Carbonyl]Amino]-, Phenylmethyl Ester is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency meet the exacting standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee traceability and compliance with your internal quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound is compatible with strong acids and organic solvents but should be kept away from incompatible materials. For long-term storage, consider inert atmosphere conditions to maximize stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.