Description

tert-Butyl 7-Azaspiro[3.5]Nonan-2-Ylcarbamate is a high-value, nitrogen-containing heterocyclic building block used in advanced organic synthesis. This compound is critical for medicinal chemistry research and development, serving as a key intermediate in the creation of novel pharmaceutical candidates. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to introduce complex spirocyclic and protected amine motifs into their target molecules.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used in scaffold hopping and lead optimization to explore structure-activity relationships (SAR) due to its rigid spirocyclic and protected amine functionality.
• Proteolysis Targeting Chimera (PROTAC) Development: Serves as a component for constructing linkers or warheads in bifunctional degrader molecules.
• Agrochemical Synthesis: Intermediate in the development of novel herbicides, fungicides, and insecticides with complex molecular architectures.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects at various scales.

Basic Information

Product Name	tert-Butyl 7-Azaspiro[3.5]Nonan-2-Ylcarbamate
CAS No.	147611-03-8
Molecular Formula	C₁₃H₂₄N₂O₂
Molecular Weight	240.34 g/mol
Synonyms	2-[(tert-Butoxycarbonyl)amino]-7-azaspiro[3.5]nonane; 7-Azaspiro[3.5]nonan-2-amine, N-BOC-; Boc-7-Azaspiro[3.5]nonan-2-amine; tert-Butyl (7-azaspiro[3.5]nonan-2-yl)carbamate; N-Boc-7-Azaspiro[3.5]nonan-2-amine; 2-(Boc-amino)-7-azaspiro[3.5]nonane; Boc-Protected 7-Azaspiro[3.5]nonan-2-amine; 147611-03-8
EINECS	Contact for details

Quality Control

Our tert-Butyl 7-Azaspiro[3.5]Nonan-2-Ylcarbamate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with detailed specifications for every shipment, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.