Description

6-(Benzyloxycarbonyl)-6-Azaspiro[2.5]Octane-1-Carboxylic Acid is a high-value, protected amino acid derivative featuring a unique spirocyclic structure. This compound serves as a critical advanced pharmaceutical intermediate (API) and a versatile building block in sophisticated organic synthesis. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutics, particularly for constructing complex molecular architectures in drug discovery programs.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel active pharmaceutical ingredients (APIs) and investigational new drugs.
• Peptidomimetics & Constrained Peptides: Used to introduce conformational rigidity into peptide backbones, enhancing stability and biological activity.
• Protease Inhibitor Development: Employed in the research and synthesis of potential inhibitors for various enzymatic targets.
• Chemical Biology & Probe Synthesis: Serves as a scaffold for creating molecular probes to study biological pathways and protein function.
• Academic & Industrial R&D: Utilized in methodological chemistry research and the development of new synthetic routes for complex heterocycles.
• Custom Synthesis & Contract Manufacturing: A starting material for the custom production of specialized fine chemicals and bespoke molecular entities.

Basic Information

Product Name	6-(Benzyloxycarbonyl)-6-Azaspiro[2.5]Octane-1-Carboxylic Acid
CAS No.	147610-85-3
Molecular Formula	C15H17NO4
Molecular Weight	275.30 g/mol
Synonyms	1-Carboxy-6-(benzyloxycarbonyl)-6-azaspiro[2.5]octane; 6-Azaspiro[2.5]octane-1-carboxylic acid, 6-[(phenylmethoxy)carbonyl]-; Z-6-Azaspiro[2.5]octane-1-carboxylic acid; Cbz-6-Azaspiro[2.5]octane-1-carboxylic acid; (1-Carboxy-6-azaspiro[2.5]oct-6-yl)carbamic acid benzyl ester; 6-N-Cbz-6-azaspiro[2.5]octane-1-carboxylic acid; Protected 6-azaspiro[2.5]octane amino acid
EINECS	Contact for details

Quality Control

Our 6-(Benzyloxycarbonyl)-6-Azaspiro[2.5]Octane-1-Carboxylic Acid is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the exacting standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.