Description

3,4,5-Trimethoxyphenyl-Isocyanide is a versatile and highly reactive organic building block, specifically an aryl isocyanide derivative. Its value lies in its role as a critical precursor in multi-component reactions and metal-catalyzed transformations, enabling the efficient synthesis of complex heterocyclic scaffolds. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for constructing complex nitrogen-containing heterocycles found in drug candidates.
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides through isocyanide-based multicomponent reactions.
• Ligand Precursor: Serves as a starting material for the synthesis of specialized isocyanide ligands used in organometallic chemistry and catalysis.
• Material Science Research: Employed in the creation of functional polymers and smart materials via polymerization reactions.
• Chemical Biology Probes: Utilized in bioorthogonal chemistry and for labeling biomolecules due to its unique reactivity.
• Academic & R&D: A fundamental reagent in organic synthesis laboratories for methodology development and discovery chemistry.

Basic Information

Product Name	3,4,5-Trimethoxyphenyl-Isocyanide
CAS No.	147492-94-2
Molecular Formula	C10H11NO3
Molecular Weight	193.20 g/mol
Synonyms	1-Isocyano-3,4,5-trimethoxybenzene; 3,4,5-Trimethoxybenzene Isocyanide; 3,4,5-Trimethoxyphenyl Isonitrile; (3,4,5-Trimethoxyphenyl)isocyanide; NSC 405124; 3,4,5-Trimethoxy Phenyl Isocyanide
EINECS	Contact for details

Quality Control

Our 3,4,5-Trimethoxyphenyl-Isocyanide is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and FTIR, to ensure high purity and consistent performance. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C or as specified on the label. This compound is easily oxidized and should be handled with care to minimize exposure to air and moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.