Description

Mgitc [Malachite Green Isothiocyanate] is a reactive dye intermediate and a key chemical building block derived from the triphenylmethane class. Its primary value lies in its isothiocyanate functional group, which enables covalent conjugation to biomolecules like proteins and antibodies for labeling and detection applications. This compound is essential for researchers and manufacturers in the life sciences, diagnostics, and analytical chemistry sectors who require high-purity, reliable reagents for fluorescence-based assays and histological staining.

Application

• Fluorescent Labeling Reagent: Covalently binds to proteins, antibodies, and other amines for use in fluorescence microscopy (FLM), flow cytometry, and immunoassays.
• Bioconjugation & Probe Synthesis: Serves as a critical linker for creating fluorescent probes, biosensors, and targeted imaging agents in biomedical research.
• Histology & Pathology Staining: Used in specialized staining protocols, often as a component or derivative in techniques for tissue and cellular analysis.
• Protein Detection & Quantification: Employed in assay development for the detection and quantification of specific proteins or enzymatic activities.
• Diagnostic Kit Manufacturing: An important raw material for producing components of in-vitro diagnostic (IVD) kits and clinical test reagents.
• Chemical Biology Research: Utilized in studying protein interactions, localization, and function through fluorescence tagging.

Basic Information

Product Name	Mgitc [Malachite Green Isothiocyanate]
CAS No.	147492-82-8
Molecular Formula	C23H23N3S
Molecular Weight	373.51 g/mol
Synonyms	Malachite Green Isothiocyanate; MGITC; [4-[[4-(Dimethylamino)phenyl]-phenylmethylene]-N-methylcyclohexa-2,5-dien-1-ylidene]dimethylammonium Isothiocyanate; Brilliant Green Isothiocyanate analogue; C.I. 42000 Isothiocyanate derivative; Triphenylmethane dye isothiocyanate; Protein labeling dye MG-ITC; Fluorescent probe precursor MGITC
EINECS	Contact for details

Quality Control

Our Mgitc [Malachite Green Isothiocyanate] is produced under strict quality management systems to ensure batch-to-batch consistency and high performance in sensitive applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity, spectrophotometric analysis, and functional group verification. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	Dark green to blue-green powder or crystals
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95% (Typical 97-99%)
Loss on Drying	≤ 2.0 %
Solubility	Soluble in DMSO, DMF; sparingly soluble in water
Functional Activity	Conjugation efficiency confirmed by standard protein labeling test

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.