Description

Carbamic Acid, (1-Methyl-4-Oxo-2-Butenyl)-, 1,1-Dimethylethyl Ester, [S-(E)]- is a specialized chiral building block and protected amino acid derivative of significant interest in advanced organic synthesis. This compound is valued for its role as a key intermediate in the production of complex pharmaceutical molecules, particularly those requiring specific stereochemistry. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and fine chemical industries for developing active pharmaceutical ingredients (APIs) and novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of protease inhibitors and other biologically active compounds.
• Peptidomimetics Research: Used in the design and construction of peptide analogs and mimetics for drug discovery programs.
• Asymmetric Synthesis: Serves as a starting material or intermediate in catalytic asymmetric reactions to introduce stereogenic centers.
• API Development: Employed in the multi-step synthesis of complex target molecules during preclinical and process development stages.
• Chemical Biology Probes: Useful for creating labeled or modified amino acid derivatives for studying biological mechanisms.
• Fine Chemical Production: Acts as a building block for high-value, low-volume specialty chemicals used in various advanced applications.

Basic Information

Product Name	Carbamic Acid, (1-Methyl-4-Oxo-2-Butenyl)-, 1,1-Dimethylethyl Ester, [S-(E)]-
CAS No.	147317-32-6
Molecular Formula	C11H19NO3
Molecular Weight	213.27 g/mol
Synonyms	(S,E)-tert-Butyl (1-methyl-4-oxobut-2-en-1-yl)carbamate; (S,E)-N-Boc-2-Amino-3-buten-2-ol; (S,E)-N-(tert-Butoxycarbonyl)-2-amino-3-buten-2-ol; (2S)-2-[(tert-Butoxycarbonyl)amino]but-3-en-2-ol (enol form); Boc-L-2-Amino-3-buten-2-ol (E-isomer); (S)-tert-Butyl (1-methyl-4-oxobut-2-enyl)carbamate; (S,E)-Boc-Amino-3-buten-2-ol; Chiral N-Boc protected amino alcohol derivative.
EINECS	Contact for details

Quality Control

Our production of Carbamic Acid, (1-Methyl-4-Oxo-2-Butenyl)-, 1,1-Dimethylethyl Ester, [S-(E)]- adheres to stringent quality protocols to ensure high chemical purity and stereochemical integrity suitable for research and cGMP manufacturing. Each batch is characterized by advanced analytical techniques including chiral HPLC, NMR, and mass spectrometry. Certificates of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles are provided to guarantee compliance with your specific research or development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. For long-term storage, consider using a desiccator or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.