Description

Aspartic Acid, n-[(1,1-Dimethylethoxy)Carbonyl]-, 4-(Phenylmethyl) Ester is a protected amino acid derivative, specifically a Boc-protected aspartic acid benzyl ester. This compound is a crucial building block in organic synthesis, designed to facilitate the controlled construction of peptides and complex molecules. It is primarily needed by pharmaceutical researchers and fine chemical manufacturers engaged in the development of APIs, bioactive peptides, and other specialized organic compounds.

Application

• Peptide Synthesis: A key protected intermediate for the solid-phase and solution-phase synthesis of peptides containing aspartic acid residues.
• Pharmaceutical Intermediates: Serves as a critical building block in the research and production of active pharmaceutical ingredients (APIs) and drug candidates.
• Bioconjugation & Linker Chemistry: Used in the preparation of modified peptides, protein conjugates, and molecular probes for biochemical research.
• Fine Chemical Production: Employed as a specialized synthon in the multi-step synthesis of complex organic molecules for agrochemicals and materials science.
• Academic & Industrial R&D: Essential for research laboratories focusing on medicinal chemistry, chemical biology, and novel synthetic methodologies.

Basic Information

Product Name	Aspartic Acid, n-[(1,1-Dimethylethoxy)Carbonyl]-, 4-(Phenylmethyl) Ester
CAS No.	147291-69-8
Molecular Formula	C16H21NO6
Molecular Weight	323.34 g/mol
Synonyms	Boc-Asp(OBzl)-OH; N-Boc-L-aspartic acid 4-benzyl ester; (2S)-2-[(tert-Butoxycarbonyl)amino]butanedioic acid 4-benzyl ester; Boc-Aspartic acid β-benzyl ester; tert-Butyloxycarbonyl-L-aspartic acid 4-benzyl ester; N-(tert-Butoxycarbonyl)-L-aspartic acid 4-benzyl ester; L-Aspartic acid, N-[(1,1-dimethylethoxy)carbonyl]-, 4-(phenylmethyl) ester; Boc-L-Asp(OBzl)-OH
EINECS	Contact for details

Quality Control

Our Boc-protected amino acid derivatives are manufactured under strict quality systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral analysis to ensure enantiomeric integrity, meeting the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and specific impurities is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation [α]	Contact for details
Chiral Purity (HPLC)	≥99.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.