Description

(2S,5S)-D-Menthol-5-(Acetyloxy)-1,3-Oxathiolane-2-Carboxylate is a high-purity chiral building block and synthetic intermediate of significant interest in advanced organic synthesis. Its value lies in its defined stereochemistry and functional groups, which are crucial for constructing complex molecules with specific three-dimensional architectures. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new therapeutic agents, particularly for antiviral and other small-molecule drugs.
• Asymmetric Synthesis: Used as a building block in stereoselective chemical reactions to introduce specific chiral centers into target molecules.
• Agrochemical Research: Employed in the synthesis of novel, enantiomerically pure pesticides and herbicides where biological activity is stereospecific.
• Flavor and Fragrance Chemistry: Potential use in the synthesis of complex, high-value chiral aroma chemicals derived from menthol.
• Academic & Process Chemistry: A valuable reagent for methodological studies in organic chemistry and for scaling up synthetic routes in process development.
• Ligand and Catalyst Preparation: Can be utilized in the synthesis of chiral ligands or organocatalysts for use in catalytic asymmetric transformations.

Basic Information

Product Name	(2S,5S)-D-Menthol-5-(Acetyloxy)-1,3-Oxathiolane-2-Carboxylate
CAS No.	147126-68-9
Molecular Formula	C16H24O5S
Molecular Weight	328.42 g/mol
Synonyms	(-)-Menthyl (2S,5S)-5-Acetoxy-1,3-oxathiolane-2-carboxylate; D-Menthol 5-Acetoxy-1,3-oxathiolane-2-carboxylate; (2S,5S)-5-(Acetyloxy)-1,3-oxathiolane-2-carboxylic acid (1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl ester; LAMV (common abbreviation); Oxathiolane carboxylate menthol ester.
EINECS	Contact for details

Quality Control

Our (2S,5S)-D-Menthol-5-(Acetyloxy)-1,3-Oxathiolane-2-Carboxylate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure high chemical and enantiomeric purity suitable for research and development applications. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This product is light-sensitive and should be stored away from direct light exposure.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% de
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.