Description

(S)-Methyl 2-(tert-Butoxycarbonylamino)-3-Cyanopropanoate is a high-value, non-natural amino acid derivative featuring a cyano group and a Boc-protected amine. This compound is a critical chiral building block in organic synthesis, prized for its versatility in constructing complex molecular architectures. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers for the development of active pharmaceutical ingredients (APIs), peptide mimetics, and other biologically active compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of protease inhibitors, enzyme inhibitors, and other novel therapeutic agents.
• Peptidomimetics Synthesis: Used to incorporate constrained, non-proteinogenic amino acid residues into peptide chains to enhance stability and bioactivity.
• Chemical Biology Probes: Serves as a precursor for labeled compounds and probes used in drug discovery and mechanism-of-action studies.
• Agrochemical Research: Employed in the development of advanced, chiral active ingredients with specific modes of action.
• Academic & Contract Research: Essential for methodological development in asymmetric synthesis and medicinal chemistry projects.

Basic Information

Product Name	(S)-Methyl 2-(tert-Butoxycarbonylamino)-3-Cyanopropanoate
CAS No.	147091-71-2
Molecular Formula	C10H16N2O4
Molecular Weight	228.25 g/mol
Synonyms	Boc-L-β-Cyanoalanine methyl ester; (S)-Methyl 3-cyano-2-((tert-butoxycarbonyl)amino)propanoate; Methyl (2S)-2-[(tert-butoxycarbonyl)amino]-3-cyanopropanoate; L-β-Cyanoalanine, N-Boc-, methyl ester; Boc-β-CN-Ala-OMe; Boc-L-Cya(CN)-OH methyl ester; (S)-2-(Boc-amino)-3-cyanopropionic acid methyl ester
EINECS	Contact for details

Quality Control

Our production of (S)-Methyl 2-(tert-Butoxycarbonylamino)-3-Cyanopropanoate adheres to stringent quality management protocols to ensure batch-to-batch consistency and high chiral purity. All material is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity (typically by HPLC), chiral purity, and identification data. We support cGMP-compliant manufacturing for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is moisture-sensitive (hygroscopic); ensure containers are sealed under inert atmosphere after opening to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.