Description

(R)-A-Isothiocyanato-Benzenepropanoic Acid Methyl Ester is a high-purity chiral building block and synthetic intermediate of significant value in advanced organic synthesis. Its isothiocyanate functional group and chiral center make it a versatile precursor for constructing complex molecules with defined stereochemistry. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of potential drug candidates, including enzyme inhibitors and receptor modulators.
• Agrochemical Research: Used in the development of novel pesticides and herbicides where specific stereochemistry is crucial for biological activity.
• Peptidomimetic Synthesis: Serves as a building block for creating peptide analogs and isosteres via reactions with amines.
• Ligand and Catalyst Development: Employed in the preparation of chiral ligands for asymmetric catalysis and metal complexes.
• Chemical Biology Probes: Utilized to create activity-based probes for studying enzyme function and protein labeling.
• Material Science: A potential monomer or cross-linking agent in the synthesis of specialized polymers.

Basic Information

Product Name	(R)-A-Isothiocyanato-Benzenepropanoic Acid Methyl Ester
CAS No.	147091-08-5
Molecular Formula	C11H11NO2S
Molecular Weight	221.27 g/mol
Synonyms	(R)-Methyl 3-Isothiocyanato-3-phenylpropanoate; (R)-Methyl 3-Phenyl-3-isothiocyanatopropanoate; (R)-3-Isothiocyanato-3-phenylpropionic Acid Methyl Ester; Methyl (R)-3-Isothiocyanato-3-phenylpropionate; (R)-α-Isothiocyanatobenzene propanoic acid methyl ester; (R)-β-Phenyl-β-isothiocyanatopropionic Acid Methyl Ester
EINECS	Contact for details

Quality Control

Our (R)-A-Isothiocyanato-Benzenepropanoic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing purity, enantiomeric excess, and other critical parameters is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid or clear to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.