Description

4-[[4-[[4-[Bis(2-Chloroethyl)Amino]Benzoyl]Amino]-1-Methyl-Imidazole-2-Carbonyl]Amino]-n-(2-Dimethylaminoethyl)-1-Methyl-Imidazole-2-Carboxamide is a sophisticated nitrogen mustard derivative and a key synthetic intermediate in advanced pharmaceutical research. This compound matters for its role as a critical building block in the development of novel targeted chemotherapeutic agents and other biologically active molecules. Pharmaceutical R&D laboratories and fine chemical manufacturers specializing in oncology drug discovery are the primary users of this high-purity intermediate.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel nitrogen mustard-based chemotherapeutic agents and targeted cancer therapies.
• Oncology Drug Discovery: Used in research and development for creating new alkylating agents designed for improved efficacy and reduced side effects.
• Bioconjugation Chemistry: Acts as a reactive moiety for linking cytotoxic payloads to antibodies, peptides, or other targeting ligands in Antibody-Drug Conjugate (ADC) development.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to explore new pharmacophores and optimize drug candidates.
• Fine Chemical Synthesis: Utilized as a specialized building block for constructing complex heterocyclic compounds with potential biological activity.
• Biochemical Probe Development: Can be used to create tools for studying DNA alkylation mechanisms and cellular response pathways.

Basic Information

Item	Details
Product Name	4-[[4-[[4-[Bis(2-Chloroethyl)Amino]Benzoyl]Amino]-1-Methyl-Imidazole-2-Carbonyl]Amino]-n-(2-Dimethylaminoethyl)-1-Methyl-Imidazole-2-Carboxamide
CAS No.	147056-64-2
Molecular Formula	C27H36Cl2N10O3
Molecular Weight	619.55 g/mol
Synonyms	4-[[4-[[4-[Bis(2-chloroethyl)amino]benzoyl]amino]-1-methyl-1H-imidazole-2-carbonyl]amino]-N-[2-(dimethylamino)ethyl]-1-methyl-1H-imidazole-2-carboxamide; Nitrogen Mustard Imidazole Carboxamide Derivative; 147056-64-2; 4-[[4-[[4-[Bis(2-Chloroethyl)Amino]Benzoyl]Amino]-1-Methyl-Imidazole-2-Carbonyl]Amino]-N-(2-Dimethylaminoethyl)-1-Methyl-Imidazole-2-Carboxamide; Mustard-Linked Imidazole Bis-Carboxamide
EINECS	Contact for details

Quality Control

Our 4-[[4-[[4-[Bis(2-Chloroethyl)Amino]Benzoyl]Amino]-1-Methyl-Imidazole-2-Carbonyl]Amino]-n-(2-Dimethylaminoethyl)-1-Methyl-Imidazole-2-Carboxamide is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot undergoes comprehensive analytical testing including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) documenting identity, purity, and all relevant specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Retention time corresponds to reference standard
Identification (NMR)	Spectrum consistent with structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.