Description

D-Erythro-Pentonic Acid, 2,5-Anhydro-3-Deoxy-3-Methyl-, Methyl Ester, (2Xi)- is a specialized chiral building block and synthetic intermediate of significant interest in advanced organic synthesis. This compound matters for its role in constructing complex molecular architectures, particularly in the development of nucleoside analogs and carbohydrate-based pharmaceuticals. It is primarily needed by research institutions and pharmaceutical companies engaged in the synthesis of antiviral agents, enzyme inhibitors, and other bioactive molecules where precise stereochemistry is critical.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of nucleoside and nucleotide analogs with potential antiviral or anticancer activity.
• Carbohydrate Chemistry Research: Used in academic and industrial labs to study modified sugar chemistry and to synthesize novel glycomimetics.
• Enzyme Inhibitor Synthesis: Serves as a precursor in the creation of transition-state analogs designed to inhibit specific glycosidases or other carbohydrate-processing enzymes.
• Chemical Biology Probes: Employed in the synthesis of labeled or tagged compounds for investigating biological pathways and mechanisms.
• Process Chemistry Development: Used in scaling up synthetic routes for active pharmaceutical ingredients (APIs) that require this specific stereochemical framework.
• Asymmetric Synthesis: Acts as a starting material or intermediate in catalytic asymmetric reactions to introduce defined chiral centers.

Basic Information

Product Name	D-Erythro-Pentonic Acid, 2,5-Anhydro-3-Deoxy-3-Methyl-, Methyl Ester, (2Xi)-
CAS No.	146820-83-9
Molecular Formula	C7H12O4
Molecular Weight	160.17 g/mol
Synonyms	Methyl 2,5-anhydro-3-deoxy-3-methyl-D-erythro-pentonate; (2R,4R)-Tetrahydro-4-methyl-2-furancarboxylic acid methyl ester; 3-Deoxy-3-methyl-D-ribono-1,4-lactone methyl ester; Methyl 3-deoxy-3-methyl-D-ribonate 1,4-lactone; 2,5-Anhydro-3-deoxy-3-methyl-D-ribonic acid methyl ester; D-erythro-Pentonic acid, 2,5-anhydro-3-deoxy-3-methyl-, methyl ester
EINECS	Contact for details

Quality Control

Our D-Erythro-Pentonic Acid, 2,5-Anhydro-3-Deoxy-3-Methyl-, Methyl Ester, (2Xi)- is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and pharmaceutical development. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.