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9H-Fluoren-9-Ylmethyln-[(2S)-1-Oxo-3-Phenylpropan-2-Yl]Carbamate CAS NO 146803-43-2


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CAS No.:146803-43-2

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

9H-Fluoren-9-Ylmethyln-[(2S)-1-Oxo-3-Phenylpropan-2-Yl]Carbamate is a specialized, high-purity chemical intermediate of significant importance in advanced organic synthesis. This compound is valued for its role as a key building block in the production of complex molecules, particularly in the pharmaceutical sector. It is primarily needed by research institutions and manufacturers engaged in the development of peptide-based therapeutics, active pharmaceutical ingredients (APIs), and other fine chemicals.

Application

  • Pharmaceutical Intermediate: A critical building block in the synthesis of peptide drugs and other complex active pharmaceutical ingredients (APIs).
  • Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis as a protected amino acid derivative.
  • Bioconjugation: Serves as a reagent for linking molecules in the development of antibody-drug conjugates (ADCs) and other bioconjugates.
  • Organic & Medicinal Chemistry Research: Employed in research laboratories for the design and creation of novel chemical entities and drug candidates.
  • Fine Chemical Production: Utilized in the multi-step synthesis of specialty chemicals requiring high stereochemical purity.

Basic Information

Product Name 9H-Fluoren-9-Ylmethyln-[(2S)-1-Oxo-3-Phenylpropan-2-Yl]Carbamate
CAS No. 146803-43-2
Molecular Formula C25H21NO4
Molecular Weight 399.44 g/mol
Synonyms Fmoc-L-Phenylalaninol; N-(9-Fluorenylmethoxycarbonyl)-L-phenylalaninol; Fmoc-Phe-ol; (2S)-2-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-3-phenylpropan-1-ol; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-phenylalaninol; Fmoc-Phenylalaninol; L-Phenylalaninol, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-; N-Fmoc-L-phenylalaninol
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Quality Control

Our 9H-Fluoren-9-Ylmethyln-[(2S)-1-Oxo-3-Phenylpropan-2-Yl]Carbamate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral purity verification, to ensure it meets the high standards required for pharmaceutical R&D and production. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant or inert atmosphere conditions.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (HPLC) Retention time matches reference standard
Assay (HPLC) ≥ 98.0%
Chiral Purity (HPLC) ≥ 99.0% (L-isomer)
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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