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7-Amino-4-(2,5,8-Trioxanonyl)Coumarin CAS NO 146773-33-3


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CAS No.:146773-33-3

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

7-Amino-4-(2,5,8-Trioxanonyl)Coumarin is a specialized functionalized coumarin derivative, a key intermediate in the synthesis of advanced fluorescent probes and labeling reagents. Its value lies in its unique molecular structure, which combines a reactive amino group with a hydrophilic trioxanonyl chain, enabling precise conjugation and enhanced solubility in aqueous systems. This compound is essential for researchers and manufacturers in the life sciences and diagnostics sectors, particularly for developing sensitive assays, bioimaging agents, and novel sensor materials.

Application

  • Fluorescent Probe Synthesis: A critical building block for creating highly specific fluorescent tags and sensors for biological targets.
  • Bioconjugation & Labeling: Used to label antibodies, proteins, peptides, and oligonucleotides for detection and imaging applications.
  • Diagnostic Assay Development: Integral to the production of reagents for ELISA, flow cytometry, and other immunoassay platforms.
  • Cell & Tissue Imaging: Serves as a precursor for dyes used in fluorescence microscopy and in vivo imaging studies.
  • Chemical Biology Research: Employed in the design of activity-based probes to study enzyme function and cellular processes.
  • Material Science: Used in the development of smart polymeric materials and sensors with optical reporting capabilities.
  • Pharmaceutical Research: Acts as an intermediate in the discovery and development of new therapeutic agents.

Basic Information

Product Name 7-Amino-4-(2,5,8-Trioxanonyl)Coumarin
CAS No. 146773-33-3
Molecular Formula C₁₈H₂₅NO₆
Molecular Weight 351.40 g/mol
Synonyms 7-Amino-4-(2,5,8-trioxanonyl)-2H-chromen-2-one; 7-Amino-4-(3,6,9-trioxadecyl)coumarin; 4-(2,5,8-Trioxanonyl)-7-aminocoumarin; AMCA-ON; AMCA Trioxanonyl Ether; 7-Amino-4-(3,6,9-trioxadecyl)-2H-1-benzopyran-2-one; Amino Methyl Coumarin Acetic Acid derivative (trioxanonyl chain)
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Quality Control

Our 7-Amino-4-(2,5,8-Trioxanonyl)Coumarin is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity, suitable for sensitive research and development applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as purity, identity, and impurity profiles. Our quality commitment aligns with the standards expected in fine chemical and bioconjugate synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and performance. For long-term storage, consider using desiccants.

Specification

Item Specification
Appearance Yellow to orange powder or crystalline solid
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 95%
Water Content (KF) ≤ 2.0%
Heavy Metals ≤ 20 ppm
Residual Solvents (GC) Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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