Description

Diethyl [4-(Prop-2-Yn-1-Yloxy)Benzylidene]Propanedioate is a specialized organic compound featuring a benzylidene malonate core functionalized with a propargyl ether group. This unique molecular architecture makes it a valuable versatile building block and key intermediate in advanced synthetic chemistry. It is primarily sought after by R&D and production chemists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecules, including potential active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly those requiring alkyne or benzylidene functionalities for further coupling reactions (e.g., Click chemistry).
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators where its reactive sites allow for structural diversification.
• Material Science Research: Acts as a monomer or cross-linking agent in the development of specialty polymers, resins, and advanced organic materials with tailored properties.
• Organic Synthesis Building Block: Employed in academic and industrial laboratories for constructing complex heterocycles and other sophisticated organic frameworks via Knoevenagel condensation and subsequent transformations.
• Liquid Crystal & OLED Material Precursor: Investigated for use in creating organic electronic materials due to its conjugated system and potential for functionalization.

Basic Information

Product Name	Diethyl [4-(Prop-2-Yn-1-Yloxy)Benzylidene]Propanedioate
CAS No.	146763-69-1
Molecular Formula	C₁₇H₁₈O₅
Molecular Weight	302.32 g/mol
Synonyms	Diethyl (4-Prop-2-yn-1-yloxybenzylidene)malonate; Diethyl 2-[(4-(2-Propynyloxy)phenyl)methylene]malonate; Propanedioic acid, 2-[(4-(2-propyn-1-yloxy)phenyl)methylene]-, diethyl ester; 4-(Prop-2-yn-1-yloxy)benzylidenemalonic acid diethyl ester; Diethyl (4-(prop-2-ynyloxy)benzylidene)malonate; (4-Propargyloxybenzylidene)malonic Acid Diethyl Ester; Diethyl α-[(4-(prop-2-yn-1-yloxy)phenyl)]methylidenemalonate
EINECS	Contact for details

Quality Control

Our production of Diethyl [4-(Prop-2-Yn-1-Yloxy)Benzylidene]Propanedioate adheres to stringent internal quality protocols to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques including HPLC, GC, NMR, and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.