Description

2-Furanpropanoic Acid, α-Amino-, Methyl Ester, (αs)- is a specialized chiral building block and intermediate of significant interest in advanced organic synthesis. This compound matters for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and fine chemicals. It is needed by research institutions, pharmaceutical companies, and fine chemical manufacturers focused on peptidomimetics, heterocyclic chemistry, and the synthesis of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, particularly for APIs targeting neurological and metabolic disorders.
• Peptidomimetic Synthesis: Used to incorporate furan-based amino acid analogs into peptide chains to modify stability, bioavailability, and biological activity.
• Asymmetric Synthesis: Serves as a building block in catalytic asymmetric reactions to create enantiomerically pure compounds.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, agrochemical intermediates, and advanced materials.
• Academic & Industrial Research: A valuable reagent for methodological development in organic chemistry and medicinal chemistry programs.
• Ligand and Catalyst Development: Potential use in the design of novel chiral ligands for metal-catalyzed transformations.

Basic Information

Product Name	2-Furanpropanoic Acid, α-Amino-, Methyl Ester, (αs)-
CAS No.	146725-85-1
Molecular Formula	C9H11NO4
Molecular Weight	197.19 g/mol
Synonyms	(S)-2-Amino-3-(2-furyl)propanoic acid methyl ester; Methyl (S)-2-amino-3-(furan-2-yl)propanoate; (S)-α-Amino-2-furanpropanoic acid methyl ester; L-2-Furylalanine methyl ester; (S)-3-(2-Furyl)alanine methyl ester; Methyl 2-amino-3-(2-furyl)propanoate; Furan-2-yl-L-alanine methyl ester; (αS)-α-Amino-2-furanpropanoic acid methyl ester
EINECS	Contact for details

Quality Control

Our 2-Furanpropanoic Acid, α-Amino-, Methyl Ester, (αs)- is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and fine chemical synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.