Description

Ethyl (S)-A-Amino-2-Thiophenepropanoate Hcl CAS NO 146684-57-3 is a high-purity chiral building block and amino acid derivative. This compound is a critical intermediate in the synthesis of complex pharmaceutical molecules, particularly those targeting neurological and metabolic disorders. It is essential for research and development chemists in the pharmaceutical and biotechnology industries who require enantiomerically pure intermediates for drug discovery and process development.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the production of active pharmaceutical ingredients (APIs) with specific stereochemistry.
• Protease Inhibitor Synthesis: Used in the research and development of novel protease inhibitors for therapeutic applications.
• Peptidomimetics Development: Serves as a constrained amino acid analog in the design of peptide-like drug candidates with improved metabolic stability.
• Asymmetric Synthesis: Employed as a starting material or auxiliary in catalytic asymmetric reactions to construct complex molecular architectures.
• Medicinal Chemistry Research: A valuable tool for structure-activity relationship (SAR) studies in early-stage drug discovery programs.
• Reference Standard: Used as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	Ethyl (S)-A-Amino-2-Thiophenepropanoate Hcl
CAS No.	146684-57-3
Molecular Formula	C9H14ClNO2S
Molecular Weight	235.73 g/mol
Synonyms	(S)-Ethyl 2-amino-3-(2-thienyl)propanoate hydrochloride; L-2-Thienylalanine ethyl ester hydrochloride; Ethyl (S)-2-amino-3-(2-thienyl)propionate hydrochloride; (S)-2-Amino-3-(2-thienyl)propionic acid ethyl ester hydrochloride; Ethyl L-2-thienylalaninate hydrochloride; (S)-α-Amino-2-thiophenepropanoic acid ethyl ester hydrochloride; 2-Thienyl-L-alanine ethyl ester HCl; Ethyl (S)-2-amino-3-(thiophen-2-yl)propanoate hydrochloride
EINECS	Contact for details

Quality Control

Our Ethyl (S)-A-Amino-2-Thiophenepropanoate Hcl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.