Description

3-Hydroxy-n-Methyl-17-Aza-D-Homoandrostan-17-One-4-N,n-Bis(2-Chloroethyl)Aminophenylacetate is a complex, nitrogen-modified steroidal derivative that serves as a key advanced intermediate in pharmaceutical research and development. Its molecular architecture, featuring a chloroethylamino phenylacetate moiety, makes it a compound of significant interest for the synthesis of targeted therapeutic agents. This high-purity chemical is primarily utilized by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in developing novel steroid-based compounds for potential clinical applications.

Application

• Pharmaceutical Intermediate: A critical building block in the synthetic pathway for novel steroidal drugs and experimental therapeutics.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to develop new compounds with modified biological activity.
• Biochemical Probe Development: Serves as a precursor for creating labeled or conjugated molecules used to study biological pathways and receptor interactions.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis for producing specialized, high-value chemical entities.
• Academic Research: Utilized in university and institutional labs for advanced studies in organic synthesis and steroid chemistry.
• Preclinical Development: Supports the early-stage development of potential active pharmaceutical ingredients (APIs) requiring complex steroidal backbones.

Basic Information

Product Name	3-Hydroxy-n-Methyl-17-Aza-D-Homoandrostan-17-One-4-N,n-Bis(2-Chloroethyl)Aminophenylacetate
CAS No.	146678-52-6
Molecular Formula	C31H42Cl2N2O3
Molecular Weight	561.59 g/mol
Synonyms	4-[Bis(2-chloroethyl)amino]phenylacetate ester of 3-hydroxy-N-methyl-17-aza-D-homoandrostan-17-one; 17-Aza-D-homoandrostane derivative; Nitrogen mustard steroidal ester; 3-Hydroxy-N-methyl-17-aza-D-homoandrostan-17-one 4-[bis(2-chloroethyl)amino]phenylacetate; NSC 686108; CAS 146678-52-6; Steroidal nitrogen mustard precursor
EINECS	Contact for details

Quality Control

Our 3-Hydroxy-n-Methyl-17-Aza-D-Homoandrostan-17-One-4-N,n-Bis(2-Chloroethyl)Aminophenylacetate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for research-grade materials. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and compliance with your research protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to maintain stability. Keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Any single unknown impurity	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.